2026 ICD-10-CM Diagnosis Code Q92.1Whole chromosome trisomy, mosaicism (mitotic nondisjunction)

ICD-10-CM Codes›Q00-Q99›Q90-Q99›Q92

ICD-10-CM Q92.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q92.1 is a billable ICD-10-CM diagnosis code for whole chromosome trisomy, mosaicism (mitotic nondisjunction). It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chromosomal abnormalities.

Code Identity

ICD-10-CM Code
Q92.1
Billable Status
Yes — Valid for Submission
Code Describes
Whole chromosome trisomy, mosaicism (mitotic nondisjunction)
Short Description
Whole chromosome trisomy, mosaicism (mitotic nondisjunction)
Same as the full description in the CMS dataset.
Parent Code
Q92
Other trisomies and partial trisomies of the autosomes, not elsewhere classified

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ90-Q99Chromosomal abnormalities, not elsewhere classified
CategoryQ92Other trisomies and partial trisomies of the autosomes, not elsewhere classified
This CodeQ92.1Whole chromosome trisomy, mosaicism (mitotic nondisjunction)

Present on Admission (POA)Billing

Q92.1 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Mosaic trisomy 1 syndrome
  • Mosaic trisomy 10 syndrome
  • Mosaic trisomy 12 syndrome
  • Mosaic trisomy 14 syndrome
  • Mosaic trisomy 15 syndrome
  • Mosaic trisomy 16 syndrome
  • Mosaic trisomy 17 syndrome
  • Mosaic trisomy 2 syndrome
  • Mosaic trisomy 20 syndrome
  • Mosaic trisomy 22 syndrome
  • Mosaic trisomy 3 syndrome
  • Mosaic trisomy 4 syndrome
  • Mosaic trisomy 5 syndrome
  • Mosaic trisomy 7 syndrome
  • Mosaic trisomy 9 syndrome
  • Trisomy 10
  • Trisomy 12
  • Trisomy 22
  • Whole chromosome trisomy - mitotic nondisjunction mosaicism
  • Whole chromosome trisomy, mosaicism

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Trisomy(syndrome)
      • chromosome specified NEC
        • whole (nonsex chromosome)
          • mitotic nondisjunction
    • Trisomy(syndrome)
      • chromosome specified NEC
        • whole (nonsex chromosome)
          • mosaicism
    • Trisomy(syndrome)
      • whole chromosome
        • mitotic nondisjunction
    • Trisomy(syndrome)
      • whole chromosome
        • mosaicism

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL009
Chromosomal abnormalities
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Trisomy 10

    a chromosomal abnormality consisting of the presence of a third copy of chromosome 10 in somatic cells.

  • Trisomy 12

    a chromosomal abnormality consisting of the presence of a third copy of chromosome 12 in somatic cells.

  • Chimpanzee Trisomy 22|Chimpanzee Down Syndrome

    a condition resulting from the presence of an extra copy of chromosome 22 in chimpanzees. the condition is in many respects similar to trisomy 21 in humans.

  • Trisomy 22

    a chromosomal abnormality consisting of the presence of a third copy of chromosome 22 in somatic cells.

Patient EducationClinical

Genetic Disorders

Genetic disorders are health conditions caused by changes (also called mutations or variants) in your genes. Genes are parts of DNA found in your cells that carry instructions for how your body grows, develops, and functions. Many genes tell your body how to make proteins, which are needed for your body to work properly.

The full article covers:

  • What are genetic disorders?
  • What causes genetic disorders?
  • What are the types of genetic disorders?
  • What are the different ways a genetic disorder can be inherited?
  • How are genetic disorders diagnosed?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q92.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
758.5 Autosomal anomalies NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q92.1Overview

Is Q92.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report whole chromosome trisomy, mosaicism (mitotic nondisjunction) on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is Q92.1 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for whole chromosome trisomy, mosaicism (mitotic nondisjunction) on inpatient claims.

What is the ICD-9 equivalent of Q92.1?

Under the General Equivalence Mappings, whole chromosome trisomy, mosaicism (mitotic nondisjunction) converts to ICD-9-CM 758.5 (autosomal anomalies NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.