ICD-10-CM Code Q91

Trisomy 18 and Trisomy 13

Version 2020 Non-Billable Code

Not Valid for Submission

Q91 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of trisomy 18 and trisomy 13. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10:Q91
Short Description:Trisomy 18 and Trisomy 13
Long Description:Trisomy 18 and Trisomy 13

Consider the following ICD-10 codes with a higher level of specificity:

  • Q91.0 - Trisomy 18, nonmosaicism (meiotic nondisjunction)
  • Q91.1 - Trisomy 18, mosaicism (mitotic nondisjunction)
  • Q91.2 - Trisomy 18, translocation
  • Q91.3 - Trisomy 18, unspecified
  • Q91.4 - Trisomy 13, nonmosaicism (meiotic nondisjunction)
  • Q91.5 - Trisomy 13, mosaicism (mitotic nondisjunction)
  • Q91.6 - Trisomy 13, translocation
  • Q91.7 - Trisomy 13, unspecified

Code Classification

  • Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • Chromosomal abnormalities, not elsewhere classified (Q90-Q99)
      • Trisomy 18 and Trisomy 13 (Q91)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Genetic Disorders

Genes are the building blocks of heredity. They are passed from parent to child. They hold DNA, the instructions for making proteins. Proteins do most of the work in cells. They move molecules from one place to another, build structures, break down toxins, and do many other maintenance jobs.

Sometimes there is a mutation, a change in a gene or genes. The mutation changes the gene's instructions for making a protein, so the protein does not work properly or is missing entirely. This can cause a medical condition called a genetic disorder.

You can inherit a gene mutation from one or both parents. A mutation can also happen during your lifetime.

There are three types of genetic disorders:

  • Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example.
  • Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed. Chromosomes are the structures that hold our genes. Down syndrome is a chromosomal disorder.
  • Complex disorders, where there are mutations in two or more genes. Often your lifestyle and environment also play a role. Colon cancer is an example.

Genetic tests on blood and other tissue can identify genetic disorders.

NIH: National Library of Medicine


[Learn More]

Trisomy 18 Trisomy 18, also called Edwards syndrome, is a chromosomal condition associated with abnormalities in many parts of the body. Individuals with trisomy 18 often have slow growth before birth (intrauterine growth retardation) and a low birth weight. Affected individuals may have heart defects and abnormalities of other organs that develop before birth. Other features of trisomy 18 include a small, abnormally shaped head; a small jaw and mouth; and clenched fists with overlapping fingers. Due to the presence of several life-threatening medical problems, many individuals with trisomy 18 die before birth or within their first month. Five to 10 percent of children with this condition live past their first year, and these children often have severe intellectual disability.
[Learn More]