2026 ICD-10-CM Diagnosis Code N25.89Other disorders resulting from impaired renal tubular function

ICD-10-CM Codes›N00–N99›N25-N29›N25

ICD-10-CM N25.89
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N25.89 is a billable ICD-10-CM diagnosis code for other disorders resulting from impaired renal tubular function. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 698 through 700. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified diseases of kidney and ureters.

Code Identity

ICD-10-CM Code
N25.89
Billable Status
Yes — Valid for Submission
Code Describes
Other disorders resulting from impaired renal tubular function
Short Description
Oth disorders resulting from impaired renal tubular function
Parent Code
N25.8
Other disorders resulting from impaired renal tubular function

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN25-N29Other disorders of kidney and ureter
CategoryN25Disorders resulting from impaired renal tubular function
This CodeN25.89Other disorders resulting from impaired renal tubular function

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired magnesium-losing nephropathy
  • Central nervous system calcification, deafness, tubular acidosis, anemia syndrome
  • Distal renal tubular acidosis
  • Distal renal tubular acidosis co-occurrent with sensorineural deafness
  • Familial proximal renal tubular acidosis
  • Familial renal hypouricemia
  • Fanconi-like syndrome
  • Gitelman syndrome
  • High renal threshold for glucose
  • Hypercalcemic nephropathy
  • Hyperkalemic renal tubular acidosis
  • Hypocalciuria
  • Hypokalemia, excessive renal losses
  • Hypokalemic alkalosis
  • Hypokalemic nephropathy
  • Isolated hypercystinuria
  • Magnesium-losing nephropathy
  • Neonatal acidosis
  • Neonatal renal disorder
  • Newborn renal dysfunction
  • Osteopetrosis with renal tubular acidosis
  • Protein-losing nephropathy
  • Proximal renal tubular acidosis
  • Renal hypocalciuria
  • Renal tubular acidosis
  • Renal tubular acidosis with progressive nerve deafness
  • Transient neonatal renal tubular acidosis
  • Uremic acidosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Hypokalemic nephropathy
  • Lightwood-Albright syndrome
  • Renal tubular acidosis NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Acidosis(lactic)
      • kidney, tubular
    • Acidosis(lactic)
      • renal (hyperchloremic) (tubular)
    • Depletion
      • potassium
        • nephropathy
    • Disease, diseased
      • Lightwood's (renal tubular acidosis)
    • Disorder(of)
      • impaired renal tubular function
        • specified NEC
    • Disorder(of)
      • kidney
        • tubular function
          • specified NEC
    • Disorder(of)
      • tubulo-renal function, impaired
        • specified NEC
    • Impaired, impairment(function)
      • kidney
        • disorder resulting from
          • specified NEC
    • Impaired, impairment(function)
      • renal (acute) (chronic)
        • disorder resulting from
          • specified NEC
    • Lightwood-Albright syndrome
    • Lightwood's disease or syndrome(renal tubular acidosis)
    • Nephropathy
      • hypercalcemic
    • Nephropathy
      • hypokalemic (vacuolar)
    • Nephropathy
      • potassium depletion
    • Nephropathy
      • protein-losing
    • Nephropathy
      • water-losing
    • Nephrosis, nephrotic(Epstein's) (syndrome) (congenital)
      • osmotic (sucrose)
    • Syndrome
      • Lightwood's
    • Water-losing nephritis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN006
Other specified and unspecified diseases of kidney and ureters
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Gitelman Syndrome

    an inherited renal disorder characterized by defective nacl reabsorption in the convoluted distal kidney tubule leading to hypokalemia. in contrast with bartter syndrome, gitelman syndrome includes hypomagnesemia and normocalcemic hypocalciuria, and is caused by mutations in the thiazide-sensitive sodium-potassium-chloride symporters.

  • Autosomal Recessive Distal Renal Tubular Acidosis-4 with Hemolytic Anemia|DRTA4

    an autosomal recessive type of distal renal tubular acidosis caused by mutation(s) in the slc4a1 gene, encoding band 3 anion transport protein. additionally, it may be characterized by hemolytic anemia.

  • Distal Renal Tubular Acidosis

    failure of the renal tubules of the kidney to excrete urine of sufficient acidity, resulting in metabolic acidosis.

  • Gitelman Syndrome

    an inherited disorder caused by mutations in the slc12a3 gene. it is characterized by deficient reabsorption of electrolytes in the distal convoluted tubules of the kidneys. it results in hypochloremic metabolic alkalosis, hypokalemia, hypocalciuria, and hypomagnesemia.

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N25.89 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
588.89 Impair ren funct dis NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N25.89Overview

Is N25.89 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other disorders resulting from impaired renal tubular function on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does N25.89 group to?

When other disorders resulting from impaired renal tubular function is the principal diagnosis on an inpatient stay, it groups to MS-DRG 698, 699, 700, with relative weights from 0.6899 to 1.6544 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of N25.89?

Under the General Equivalence Mappings, other disorders resulting from impaired renal tubular function converts to ICD-9-CM 588.89 (impair ren funct dis NEC). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.