2026 ICD-10-CM Diagnosis Code N14.2Nephropathy induced by unspecified drug, medicament or biological substance

ICD-10-CM Codes›N00–N99›N10-N16›N14

ICD-10-CM N14.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N14.2 is a billable ICD-10-CM diagnosis code for nephropathy induced by unspecified drug, medicament or biological substance. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 698 through 700. Coders also document this condition as acute drug-induced tubulointerstitial nephritis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Nephritis; nephrosis; renal sclerosis.

Code Identity

ICD-10-CM Code
N14.2
Billable Status
Yes — Valid for Submission
Code Describes
Nephropathy induced by unspecified drug, medicament or biological substance
Short Description
Nephrop induced by unsp drug, medicament or biolg sub
Parent Code
N14
Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN10-N16Renal tubulo-interstitial diseases
CategoryN14Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
This CodeN14.2Nephropathy induced by unspecified drug, medicament or biological substance

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute drug-induced tubulointerstitial nephritis
  • Acute tubulointerstitial nephritis
  • Chronic drug-induced renal disease
  • Chronic drug-induced tubulointerstitial nephritis
  • Chronic toxic interstitial nephritis
  • Drug-induced membranous nephropathy
  • Drug-induced tubulointerstitial nephritis
  • Nephritis caused by drug
  • Renal hypersensitivity caused by drug

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Nephropathy
      • drug-induced
    • Nephropathy
      • toxic NEC
        • due to
          • drugs

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR GEN001
Nephritis; nephrosis; renal sclerosis
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Drug Reactions

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The full article covers:

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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N14.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
583.89 Nephritis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2023No changes
FY 2024RevisedCode revised
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N14.2Overview

Is N14.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report nephropathy induced by unspecified drug, medicament or biological substance on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does N14.2 group to?

When nephropathy induced by unspecified drug, medicament or biological substance is the principal diagnosis on an inpatient stay, it groups to MS-DRG 698, 699, 700, with relative weights from 0.6899 to 1.6544 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of N14.2?

Under the General Equivalence Mappings, nephropathy induced by unspecified drug, medicament or biological substance converts to ICD-9-CM 583.89 (nephritis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.