Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14) ICD-10-CM
The N14 code range covers drug- and heavy-metal-induced tubulo-interstitial and tubular conditions with 8 ICD-10-CM diagnosis codes. 6 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Codes in the N14 Range 8 codes · 6 billable
- N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditionsNon-billable
- N14.0 Analgesic nephropathy
- N14.1 Nephropathy induced by other drugs, medicaments and biological substancesNon-billable
- N14.11 Contrast-induced nephropathy
- N14.19 Nephropathy induced by other drugs, medicaments and biological substances
- N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
- N14.3 Nephropathy induced by heavy metals
- N14.4 Toxic nephropathy, not elsewhere classified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the N14 range.
Contrast - Induced Nephropathy
Kidney damage resulting from exposure to contrast agents.
Drug-Induced Nephropathy
Kidney damage resulting from exposure to drugs.
About the N14 Code Range
Drugs and heavy metals can cause kidney conditions involving the tubules or the tissue around them. N14 groups these conditions by the substance involved.
N14.0 identifies kidney disease caused by pain-relieving drugs. N14.1 covers other drugs, medicines and biological substances. It separates contrast-induced kidney disease at N14.11 from other substances at N14.19.
N14.2 identifies an unspecified drug, medicine or biological substance. N14.3 identifies heavy metals, while N14.4 covers toxic kidney disease not classified elsewhere.
Questions About This Page
How many billable codes are in the N14 range?
Of the 8 codes in this range, 6 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the N14 range classify?
The range classifies drug- and heavy-metal-induced tubulo-interstitial and tubular conditions. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.