Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14) ICD-10-CM
The N14 code range covers drug- and heavy-metal-induced tubulo-interstitial and tubular conditions with 8 ICD-10-CM diagnosis codes. 6 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Codes in the N14 Range 8 codes · 6 billable
- N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditionsNon-billable
- N14.0 Analgesic nephropathy
- N14.1 Nephropathy induced by other drugs, medicaments and biological substancesNon-billable
- N14.11 Contrast-induced nephropathy
- N14.19 Nephropathy induced by other drugs, medicaments and biological substances
- N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
- N14.3 Nephropathy induced by heavy metals
- N14.4 Toxic nephropathy, not elsewhere classified
About the N14 Code Range
ICD-10 code section N14 covers kidney damage caused specifically by certain drugs and heavy metals, including different types of tubulo-interstitial and tubular conditions. These codes help identify renal problems directly linked to toxic substances, differentiating from other kidney diseases.
This section includes codes such as N14.0 for analgesic nephropathy, which is kidney damage caused by long-term use of pain relievers. Synonyms such as chronic drug-induced tubulointerstitial nephritis clarify this condition. N14.1 and its subcodes (e.g., N14.11 for contrast-induced nephropathy) classify kidney disease caused by various other drugs and biological substances. N14.19 expands on nephropathies linked to drugs like penicillamine, lithium, or cyclosporine, often described as chronic drug-induced renal disease. For toxic effects from heavy metals like lead or mercury, N14.3 includes terms such as saturnine nephropathy and chronic lead nephropathy. Finally, N14.4 addresses toxic nephropathy cases that do not fit elsewhere, including oxalate and aristolochic acid nephropathies. These ICD-10 codes are essential for accurately coding kidney conditions traced to specific toxins or medications.
Questions About This Page
How many billable codes are in the N14 range?
Of the 8 codes in this range, 6 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the N14 range classify?
The range classifies drug- and heavy-metal-induced tubulo-interstitial and tubular conditions. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
