2027 ICD-10-CM Diagnosis Code M10.221Drug-induced gout, right elbow

ICD-10-CM Codes›M00–M99›M05-M14›M10

ICD-10-CM M10.221
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

M10.221 is a billable ICD-10-CM diagnosis code for drug-induced gout, right elbow. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 553 through 554. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Gout.

Code Identity

ICD-10-CM Code
M10.221
Billable Status
Yes — Valid for Submission
Code Describes
Drug-induced gout, right elbow
Short Description
Drug-induced gout, right elbow
Same as the full description in the CMS dataset.
Parent Code
M10.22
Drug-induced gout, elbow

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM05-M14Inflammatory polyarthropathies
CategoryM10Gout
This CodeM10.221Drug-induced gout, right elbow

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to M10.221: its own notes plus those printed at M10.2, M10, block M00-M25, and Chapter 13. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block M00-M25 applies to 2,249 codes
  • Disorders affecting predominantly peripheral (limb) joints

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From M10 Gout applies to 121 codes
From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From M10.2 Drug-induced gout applies to 24 codes
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
From M10 Gout applies to 121 codes
  • code to identify:
  • Autonomic neuropathy in diseases classified elsewhere (G99.0)
  • Calculus of urinary tract in diseases classified elsewhere (N22)
  • Cardiomyopathy in diseases classified elsewhere (I43)
  • Disorders of external ear in diseases classified elsewhere (H61.1-, H62.8-)
  • Disorders of iris and ciliary body in diseases classified elsewhere (H22)
  • Glomerular disorders in diseases classified elsewhere (N08)

Notes

General instructions on how these codes are used.

From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name M10.221, its category, or a range that includes it.

Excludes1 3

These codes carry an Excludes1 note naming M10.221: they are not reported together with it, unless the two conditions are unrelated.

  • E72 Other disorders of amino-acid metabolism
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • E79 Disorders of purine and pyrimidine metabolism
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • M1A Chronic gout
    gout NOS (M10.-) names M10.-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming M10.221: its condition is not part of those codes, and both may be reported when the patient has both.

  • M1A Chronic gout
    acute gout (M10.-) names M10.-, which includes this code

Code First 5

These codes say to code first a condition named in the note, and M10.221 is one of the conditions named.

  • G99.0 Autonomic neuropathy in diseases classified elsewhere
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • H22 Disorders of iris and ciliary body in diseases classified elsewhere
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • H62.8 Other disorders of external ear in diseases classified elsewhere
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • N08 Glomerular disorders in diseases classified elsewhere
    gout (M1A.-, M10.-) names M10.-, which includes this code
  • N22 Calculus of urinary tract in diseases classified elsewhere
    gout (M1A.-, M10.-) names M10.-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR MUS033
Gout
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Gout

    metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.

Patient EducationClinical

Gout

Gout is a common type of inflammatory arthritis. It causes pain, swelling, and redness in one or more joints. It usually happens as a flare, which can last for a week or two and then gets better. The flares often begin in your big toe or a lower limb.

The full article covers:

  • What is gout?
  • What causes gout?
  • Who is more likely to develop gout?
  • What are the symptoms of gout?
  • How is gout diagnosed?
  • What are the treatments for gout?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M10.221 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
274.00 Gouty arthropathy NOS
Approximate The match is approximate rather than exact.
ICD-9-CM
274.01 Acute gouty arthropathy
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About M10.221Overview

What is the ICD-10 code for drug-induced gout, right elbow?

The ICD-10-CM code for drug-induced gout, right elbow is M10.221 (sometimes written as M10221). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is M10.221 (Drug-induced gout, elbow) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report drug-induced gout, right elbow on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does M10.221 group to?

When drug-induced gout, right elbow is the principal diagnosis on an inpatient stay, it groups to MS-DRG 554, 553, with relative weights from 0.8328 to 1.2492 depending on complications. Higher weights mean higher Medicare reimbursement.

Does M10.221 need an additional code?

When the condition applies, yes. The Use Additional Code note at M10.2, which applies to M10.221, reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after M10.221.

What is the ICD-9 equivalent of M10.221?

Under the General Equivalence Mappings, drug-induced gout, right elbow converts to ICD-9-CM 274.00 (gouty arthropathy NOS) and 274.01 (acute gouty arthropathy). The mapping is approximate, so confirm the match fits the documentation.