2026 ICD-10-CM Diagnosis Code L50.5Cholinergic urticaria

ICD-10-CM Codes›L00–L99›L49-L54›L50

ICD-10-CM L50.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

L50.5 is a billable ICD-10-CM diagnosis code for cholinergic urticaria. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607. Coders also document this condition as cholinergic pruritus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Allergic reactions and Other specified inflammatory condition of skin.

Code Identity

ICD-10-CM Code
L50.5
Billable Status
Yes — Valid for Submission
Code Describes
Cholinergic urticaria
Short Description
Cholinergic urticaria
Same as the full description in the CMS dataset.
Parent Code
L50
Urticaria

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL49-L54Urticaria and erythema
CategoryL50Urticaria
This CodeL50.5Cholinergic urticaria

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cholinergic pruritus
  • Cholinergic urticaria
  • Chronic urticaria
  • Persisting cholinergic urticaria

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Urticaria
      • cholinergic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ031
Allergic reactions
Default principal diagnosis: inpatient No · outpatient No
CCSR SKN002
Other specified inflammatory condition of skin
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Chronic Urticaria

    wheals (urticaria) and/or angioedema presented with daily symptoms lasting for more than 6 weeks. it may be classified into chronic spontaneous and chronic inducible urticaria depending on whether a specific trigger can be linked to the development of vascular reaction.

Patient EducationClinical

Hives

Hives are red and sometimes itchy bumps on your skin. An allergic reaction to a drug or food usually causes them. Allergic reactions cause your body to release chemicals that can make your skin swell up in hives. People who have other allergies are more likely to get hives than other people. Other causes include infections and stress.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert L50.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
708.5 Cholinergic urticaria
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About L50.5Overview

Is L50.5 (Urticaria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cholinergic urticaria on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does L50.5 group to?

When cholinergic urticaria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, with relative weights from 0.9064 to 1.5132 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of L50.5?

Under the General Equivalence Mappings, cholinergic urticaria converts to ICD-9-CM 708.5 (cholinergic urticaria). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.