2026 ICD-10-CM Diagnosis Code L29.81Cholestatic pruritus

ICD-10-CM Codes›L00–L99›L20-L30›L29

ICD-10-CM L29.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

L29.81 is a billable ICD-10-CM diagnosis code for cholestatic pruritus. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified inflammatory condition of skin.

Code Identity

ICD-10-CM Code
L29.81
Billable Status
Yes — Valid for Submission
Code Describes
Cholestatic pruritus
Short Description
Cholestatic pruritus
Same as the full description in the CMS dataset.
Parent Code
L29.8
Other pruritus

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL20-L30Dermatitis and eczema
CategoryL29Pruritus
This CodeL29.81Cholestatic pruritus

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cholestatic pruritus

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code Also

  • , if applicable, type of liver disease

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Pruritus, pruritic(essential)
      • cholestatic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SKN002
Other specified inflammatory condition of skin
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Pruritus

    an intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

  • Pruritus Ani

    intense chronic itching in the anal area.

  • Pruritus Vulvae

    intense itching of the external female genitals.

  • Pruritic Disorder

    a skin disorder characterized by an intense itching sensation.

Code History & ChangesHistory

Replacement L29.81 replaces the following previously assigned code(s):

  • L29.8 - Other pruritus
FY 2025AddedAdded to the ICD-10-CM code setEffective October 1, 2024.
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About L29.81Overview

Is L29.81 (Other pruritus) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cholestatic pruritus on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does L29.81 group to?

When cholestatic pruritus is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, with relative weights from 0.9064 to 1.5132 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.