2027 ICD-10-CM Diagnosis Code K76.81Hepatopulmonary syndrome

ICD-10-CM Codes›K00–K95›K70-K77›K76

ICD-10-CM K76.81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

K76.81 is a billable ICD-10-CM diagnosis code for hepatopulmonary syndrome. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 205 through 206. The code is not accepted as a principal diagnosis by the Medicare Code Editor. Coders also document this condition as dilatation of pulmonary artery. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified liver disease.

For Medicare Advantage risk adjustment, K76.81 maps to CMS-HCC Category 63 (Chronic Liver Failure/End-Stage Liver Disorders) under the V28 model, adding a risk factor of about 0.962 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
K76.81
Billable Status
Yes — Valid for Submission
Code Describes
Hepatopulmonary syndrome
Short Description
Hepatopulmonary syndrome
Same as the full description in the CMS dataset.
Parent Code
Other specified diseases of liver

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK76Other diseases of liver
This CodeK76.81Hepatopulmonary syndrome

Code EditsBilling

Medicare Code Editor checks that affect claim validity for K76.81.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Medicare Risk Adjustment (HCC)Billing

K76.81 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 63— Chronic Liver Failure/End-Stage Liver Disorders
Payment HCC · PY 2027 one of 14 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.962
community, non-dual, aged · ranges 0.861–1.209 across segments
Hierarchy
Superseded by HCC 62
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 27
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 27 · ESRD (V21): HCC 27 · ESRD (V24): HCC 27
ESRD V21 weights: 0.204 dialysis, 0.863–1.028 functioning graft · ESRD V24 weights: 0.196 dialysis, 0.764–1.149 functioning graft
Part D (RxHCC)
Not mapped
K76.81 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Dilatation of pulmonary artery
  • Hepatopulmonary syndrome

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to K76.81: its own notes plus those printed at K76, block K70-K77, and Chapter 11. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block K70-K77 Diseases of liver applies to 65 codes
  • jaundice NOS (R17)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From K76 Other diseases of liver applies to 13 codes
  • alcoholic liver disease (K70.-)
  • amyloid degeneration of liver (E85.-)
  • cystic disease of liver (congenital) (Q44.6)
  • hepatic vein thrombosis (I82.0)
  • hepatomegaly NOS (R16.0)
  • pigmentary cirrhosis (of liver) (E83.110)
  • portal vein thrombosis (I81)
  • toxic liver disease (K71.-)
From Block K70-K77 Diseases of liver applies to 65 codes
From Chapter 11 (K00-K95) Diseases of the digestive system applies to 863 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Code First

The underlying condition named in the note is sequenced before this code.

  • underlying liver disease, such as:
  • alcoholic cirrhosis of liver (K70.3-)
  • cirrhosis of liver without mention of alcohol (K74.6-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Hepatopulmonary Syndrome

    a syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (hypoxemia) in the absence of intrinsic cardiopulmonary disease. this syndrome is common in the patients with liver cirrhosis or portal hypertension (hypertension, portal).

Patient EducationClinical

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K76.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.5 Hepatopulmonary syndrome
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About K76.81Overview

What is the ICD-10 code for hepatopulmonary syndrome?

The ICD-10-CM code for hepatopulmonary syndrome is K76.81 (sometimes written as K7681). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is K76.81 (Other specified diseases of liver) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatopulmonary syndrome on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does K76.81 group to?

On inpatient claims, hepatopulmonary syndrome maps to MS-DRG 206, 205, with relative weights from 0.9255 to 1.8244 depending on complications. Higher weights mean higher Medicare reimbursement.

Can K76.81 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because hepatopulmonary syndrome describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Can K76.81 be reported with R17?

Not as a rule. The Excludes1 note at block K70-K77, which applies to K76.81, lists "jaundice NOS (R17)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is K76.81?

K76.81 (hepatopulmonary syndrome) maps to CMS-HCC Category 63 (Chronic Liver Failure/End-Stage Liver Disorders), commonly written as HCC 63, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 27 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does K76.81 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, K76.81 adds a risk adjustment factor of about 0.962 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.861 to 1.209 depending on the payment segment). A more severe related category (HCC 62) supersedes it when both are reported. See the full factor table on the HCC 63 category page.