2026 ICD-10-CM Diagnosis Code K76.81Hepatopulmonary syndrome

ICD-10-CM Codes›K00–K95›K70-K77›K76

ICD-10-CM K76.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K76.81 is a billable ICD-10-CM diagnosis code for hepatopulmonary syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 205 through 206. The code is not accepted as a principal diagnosis by the Medicare Code Editor. Coders also document this condition as dilatation of pulmonary artery. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K76.81
Billable Status
Yes — Valid for Submission
Code Describes
Hepatopulmonary syndrome
Short Description
Hepatopulmonary syndrome
Same as the full description in the CMS dataset.
Parent Code
K76.8
Other specified diseases of liver

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK76Other diseases of liver
This CodeK76.81Hepatopulmonary syndrome

Code EditsBilling

Medicare Code Editor checks that affect claim validity for K76.81.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Dilatation of pulmonary artery
  • Hepatopulmonary syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code First

  • underlying liver disease, such as:
  • alcoholic cirrhosis of liver K70.3
  • cirrhosis of liver without mention of alcohol K74.6

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Syndrome
      • hepatopulmonary

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Hepatopulmonary Syndrome

    a syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (hypoxemia) in the absence of intrinsic cardiopulmonary disease. this syndrome is common in the patients with liver cirrhosis or portal hypertension (hypertension, portal).

Patient EducationClinical

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K76.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.5 Hepatopulmonary syndrome
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K76.81Overview

Is K76.81 (Other specified diseases of liver) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatopulmonary syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K76.81 group to?

On inpatient claims, hepatopulmonary syndrome maps to MS-DRG 205, 206, with relative weights from 0.9411 to 1.8310 depending on complications. Higher weights mean higher Medicare reimbursement.

Can K76.81 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because hepatopulmonary syndrome describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

What is the ICD-9 equivalent of K76.81?

Under the General Equivalence Mappings, hepatopulmonary syndrome converts to ICD-9-CM 573.5 (hepatopulmonary syndrome). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.