2027 ICD-10-CM Diagnosis Code K71.6Toxic liver disease with hepatitis, not elsewhere classified

ICD-10-CM Codes›K00–K95›K70-K77›K71

ICD-10-CM K71.6
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

K71.6 is a billable ICD-10-CM diagnosis code for toxic liver disease with hepatitis, not elsewhere classified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 441 through 443, 791, 793. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Noninfectious hepatitis.

Code Identity

ICD-10-CM Code
K71.6
Billable Status
Yes — Valid for Submission
Code Describes
Toxic liver disease with hepatitis, not elsewhere classified
Short Description
Toxic liver disease with hepatitis, not elsewhere classified
Same as the full description in the CMS dataset.
Parent Code
Toxic liver disease

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK71Toxic liver disease
This CodeK71.6Toxic liver disease with hepatitis, not elsewhere classified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Allergic hepatitis
  • Cholangiohepatitis
  • Cholestatic hepatitis
  • Drug-induced chronic hepatitis
  • Drug-induced hepatitis
  • Enflurane hepatitis
  • Enflurane poisoning
  • Halothane hepatitis
  • Hypersensitivity disease of liver caused by drug
  • Poisoning by carbamazepine
  • Poisoning by halothane
  • Toxic hepatitis
  • Toxic hepatitis due to carbamazepine

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to K71.6: its own notes plus those printed at K71, block K70-K77, and Chapter 11. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From K71 Toxic liver disease applies to 12 codes
  • drug-induced idiosyncratic (unpredictable) liver disease
  • drug-induced toxic (predictable) liver disease

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block K70-K77 Diseases of liver applies to 65 codes
  • jaundice NOS (R17)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From K71 Toxic liver disease applies to 12 codes
  • alcoholic liver disease (K70.-)
  • Budd-Chiari syndrome (I82.0)
From Block K70-K77 Diseases of liver applies to 65 codes
From Chapter 11 (K00-K95) Diseases of the digestive system applies to 863 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Code First

The underlying condition named in the note is sequenced before this code.

From K71 Toxic liver disease applies to 12 codes
  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From K71 Toxic liver disease applies to 12 codes
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name K71.6, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming K71.6: they are not reported together with it, unless the two conditions are unrelated.

  • K73 Chronic hepatitis, not elsewhere classified
    drug-induced hepatitis (chronic) (K71.-) names K71.-, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming K71.6: its condition is not part of those codes, and both may be reported when the patient has both.

  • K75 Other inflammatory liver diseases
    toxic liver disease (K71.-) names K71.-, which includes this code
  • K76 Other diseases of liver
    toxic liver disease (K71.-) names K71.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR DIG023
Noninfectious hepatitis
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Hepatitis

Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. It can damage your liver. This swelling and damage can affect how well your liver functions.

The full article covers:

  • What is hepatitis?
  • What causes hepatitis?
  • How is viral hepatitis spread?
  • Who is at risk for hepatitis?
  • What are the symptoms of hepatitis?
  • What other problems can hepatitis cause?
  • How is hepatitis diagnosed?
  • What are the treatments for hepatitis?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K71.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.3 Hepatitis NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About K71.6Overview

What is the ICD-10 code for toxic liver disease with hepatitis, not elsewhere classified?

The ICD-10-CM code for toxic liver disease with hepatitis, not elsewhere classified is K71.6 (sometimes written as K716). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is K71.6 (Toxic liver disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic liver disease with hepatitis, not elsewhere classified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does K71.6 group to?

When toxic liver disease with hepatitis, not elsewhere classified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 442, 441, 443, with relative weights from 0.6890 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Can K71.6 be reported with R17?

Not as a rule. The Excludes1 note at block K70-K77, which applies to K71.6, lists "jaundice NOS (R17)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does K71.6 need an additional code?

When the condition applies, yes. The Use Additional Code note at K71, which applies to K71.6, reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after K71.6.