2026 ICD-10-CM Diagnosis Code K71.0Toxic liver disease with cholestasis

ICD-10-CM Codes›K00–K95›K70-K77›K71

ICD-10-CM K71.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K71.0 is a billable ICD-10-CM diagnosis code for toxic liver disease with cholestasis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 441 through 443. Coders also document this condition as cholangiohepatitis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K71.0
Billable Status
Yes — Valid for Submission
Code Describes
Toxic liver disease with cholestasis
Short Description
Toxic liver disease with cholestasis
Same as the full description in the CMS dataset.
Parent Code
K71
Toxic liver disease

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK71Toxic liver disease
This CodeK71.0Toxic liver disease with cholestasis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cholangiohepatitis
  • Cholestatic hepatitis
  • Cryptogenic organizing pneumonia
  • Drug-induced cholestatic hepatitis
  • Drug-induced hepatitis
  • Idiopathic interstitial pneumonitis
  • Intrahepatic cholestasis
  • Organized pneumonia
  • Seasonal cryptogenic organizing pneumonia with biochemical cholestasis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Cholestasis with hepatocyte injury
  • 'Pure' cholestasis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Cholestasis NEC
      • with hepatocyte injury
    • Cholestasis NEC
      • pure
    • Disease, diseased
      • liver (chronic) (organic)
        • toxic
          • with
            • cholestasis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cryptogenic Organizing Pneumonia

    an interstitial lung disease of unknown etiology, occurring between 21-80 years of age. it is characterized by a dramatic onset of a pneumonia-like illness with cough, fever, malaise, fatigue, and weight loss. pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. there is excessive proliferation of granulation tissue within small airways and alveolar ducts.

  • Progressive Familial Intrahepatic Cholestasis Type 3|PFIC3

    an autosomal recessive subtype of progressive familial intrahepatic cholestasis caused by mutation(s) in the abcb4 gene, encoding phosphatidylcholine translocator abcb4.

  • ABCB11 wt Allele|ABC Member 16, MDR/TAP Subfamily Gene|ABC16|ATP Binding Cassette Subfamily B Member 11 wt Allele|ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 Gene|ATP-Binding Cassette, Subfamily B, Member 11 Gene|BRIC2|BSEP|PFIC-2|PFIC2|PGY4|Progressive Familial Intrahepatic Cholestasis 2 Gene|SPGP|Sister of P-Glycoprotein Gene

    human abcb11 wild-type allele is located in the vicinity of 2q24 and is approximately 108 kb in length. this allele, which encodes bile salt export pump protein, is involved in bile salt transport. mutation of the gene is associated with hereditary intrahepatic cholestasis.

  • Benign Recurrent Intrahepatic Cholestasis

    reappearance of cholestasis caused by obstruction within the liver by non-cancerous conditions.

  • Intrahepatic Cholestasis

    impairment of the bile flow caused by obstruction within the liver.

  • Progressive Familial Intrahepatic Cholestasis

    a genetic syndrome affecting infants and children. it is characterized by chronic intrahepatic cholestasis usually progressing to cirrhosis within the first ten years of life.

  • Recurrent Intrahepatic Cholestasis

    reappearance of cholestasis caused by obstruction within the liver.

Patient EducationClinical

Bile Duct Diseases

Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K71.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.3 Hepatitis NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K71.0Overview

Is K71.0 (Toxic liver disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic liver disease with cholestasis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K71.0 group to?

When toxic liver disease with cholestasis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 441, 442, 443, with relative weights from 0.6997 to 1.7947 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K71.0?

Under the General Equivalence Mappings, toxic liver disease with cholestasis converts to ICD-9-CM 573.3 (hepatitis NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.