2027 ICD-10-CM Diagnosis Code I67.3Progressive vascular leukoencephalopathy

ICD-10-CM Codes›I00–I99›I60-I69›I67

ICD-10-CM I67.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

I67.3 is a billable ICD-10-CM diagnosis code for progressive vascular leukoencephalopathy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 56 through 57, 974 through 976. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 175 closely related codes. Coders also document this condition as pontine autosomal dominant microangiopathy with leukoencephalopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other and ill-defined cerebrovascular disease and Other nervous system disorders (neither hereditary nor degenerative).

For Medicare Advantage risk adjustment, I67.3 maps to CMS-HCC Category 127 (Dementia, Mild or Unspecified) under the V28 model, adding a risk factor of about 0.341 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
I67.3
Billable Status
Yes — Valid for Submission
Code Describes
Progressive vascular leukoencephalopathy
Short Description
Progressive vascular leukoencephalopathy
Same as the full description in the CMS dataset.
Parent Code
Other cerebrovascular diseases

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI60-I69Cerebrovascular diseases
CategoryI67Other cerebrovascular diseases
This CodeI67.3Progressive vascular leukoencephalopathy

Medicare Risk Adjustment (HCC)Billing

I67.3 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 127— Dementia, Mild or Unspecified
Payment HCC · PY 2027 one of 65 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.341
community, non-dual, aged · ranges 0.000–0.438 across segments
Hierarchy
Superseded by HCC 125 and HCC 126
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 52
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
ESRD (V21): HCC 52 · ESRD (V24): HCC 52
ESRD V21 weights: 0.045 dialysis, 0.000–0.328 functioning graft · ESRD V24 weights: 0.042 dialysis, 0.000–0.399 functioning graft
Part D (RxHCC)
RxHCC 112 — Dementia, Except Alzheimer's Disease
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Pontine autosomal dominant microangiopathy with leukoencephalopathy
  • Small vessel cerebrovascular disease

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to I67.3: its own notes plus those printed at I67, block I60-I69, and Chapter 9. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Binswanger's disease

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From I67 Other cerebrovascular diseases applies to 17 codes
  • Occlusion and stenosis of cerebral artery causing cerebral infarction (I63.3-I63.5-)
  • Occlusion and stenosis of precerebral artery causing cerebral infarction (I63.2-)
From Block I60-I69 Cerebrovascular diseases applies to 410 codes
  • traumatic intracranial hemorrhage (S06.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From I67 Other cerebrovascular diseases applies to 17 codes
  • sequelae of the listed conditions (I69.8)
From Chapter 9 (I00-I99) Diseases of the circulatory system applies to 1,433 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block I60-I69 Cerebrovascular diseases applies to 410 codes
  • code to identify presence of:
  • alcohol abuse and dependence (F10.-)
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • hypertension (I10-I1A)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR024
Other and ill-defined cerebrovascular disease
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I67.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
046.3 Prog multifoc leukoencep
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About I67.3Overview

What is the ICD-10 code for progressive vascular leukoencephalopathy?

The ICD-10-CM code for progressive vascular leukoencephalopathy is I67.3 (sometimes written as I673). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is I67.3 (Other cerebrovascular diseases) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report progressive vascular leukoencephalopathy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does I67.3 group to?

When progressive vascular leukoencephalopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 974, 976, 975, 57, 56, with relative weights from 0.7879 to 3.0488 depending on complications. Higher weights mean higher Medicare reimbursement.

Is I67.3 a CC or MCC?

CMS lists I67.3 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 175 closely related codes in its exclusion list.

Can I67.3 be reported with a code from I63.2?

Not as a rule. The Excludes1 note at I67, which applies to I67.3, lists "Occlusion and stenosis of precerebral artery causing cerebral infarction (I63.2-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is I67.3?

I67.3 (progressive vascular leukoencephalopathy) maps to CMS-HCC Category 127 (Dementia, Mild or Unspecified), commonly written as HCC 127, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 52 under the retired V24 model. It also maps in the ESRD (V21) and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 112.

Does I67.3 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, I67.3 adds a risk adjustment factor of about 0.341 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.000 to 0.438 depending on the payment segment). A more severe related category (HCC 125 and HCC 126) supersedes it when both are reported. See the full factor table on the HCC 127 category page.