2026 ICD-10-CM Diagnosis Code I67.3Progressive vascular leukoencephalopathy

ICD-10-CM CodesI00–I99I60-I69I67

ICD-10-CM I67.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I67.3 is a billable ICD-10-CM diagnosis code for progressive vascular leukoencephalopathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 974 through 976. Coders also document this condition as pontine autosomal dominant microangiopathy with leukoencephalopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other and ill-defined cerebrovascular disease and Other nervous system disorders (neither hereditary nor degenerative).

Code Identity

ICD-10-CM Code
I67.3
Billable Status
Yes — Valid for Submission
Code Describes
Progressive vascular leukoencephalopathy
Short Description
Progressive vascular leukoencephalopathy
Same as the full description in the CMS dataset.
Parent Code
Other cerebrovascular diseases

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI60-I69Cerebrovascular diseases
CategoryI67Other cerebrovascular diseases
This CodeI67.3Progressive vascular leukoencephalopathy

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Pontine autosomal dominant microangiopathy with leukoencephalopathy
  • Small vessel cerebrovascular disease

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Binswanger's disease

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Binswanger's disease
    • Leukoencephalopathy
      • Binswanger's
    • Leukoencephalopathy
      • vascular, progressive

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR024
Other and ill-defined cerebrovascular disease
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I67.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
046.3 Prog multifoc leukoencep
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I67.3Overview

Is I67.3 (Other cerebrovascular diseases) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report progressive vascular leukoencephalopathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I67.3 group to?

When progressive vascular leukoencephalopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 974, 975, 976, with relative weights from 0.8945 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I67.3?

Under the General Equivalence Mappings, progressive vascular leukoencephalopathy converts to ICD-9-CM 046.3 (prog multifoc leukoencep). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.