2027 ICD-10-CM Diagnosis Code I49.3Ventricular premature depolarization

ICD-10-CM Codes›I00–I99›I30-I5A›I49

ICD-10-CM I49.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

I49.3 is a billable ICD-10-CM diagnosis code for ventricular premature depolarization. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 308 through 310. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Cardiac dysrhythmias.

This medical diagnosis code is frequently used in Cardiology medical specialties to designate conditions such cardiac arrhythmias (other).

Code Identity

ICD-10-CM Code
I49.3
Billable Status
Yes — Valid for Submission
Code Describes
Ventricular premature depolarization
Short Description
Ventricular premature depolarization
Same as the full description in the CMS dataset.
Parent Code
Other cardiac arrhythmias

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI30-I5AOther forms of heart disease
CategoryI49Other cardiac arrhythmias
This CodeI49.3Ventricular premature depolarization

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • ECG: ventricular ectopics
  • Electrocardiographic monomorphic premature ventricular contraction
  • Electrocardiographic polymorphic premature ventricular contraction
  • Idioventricular rhythm
  • Interpolated ventricular premature complexes
  • Multifocal premature ventricular complexes
  • Multiple premature ventricular complexes
  • Multiple ventricular interpolated complexes
  • Paired ventricular premature complexes
  • Paired ventricular premature complexes on electrocardiogram
  • Robin sequence
  • Run of ventricular premature complexes
  • Three consecutive ventricular premature complexes
  • Unifocal premature ventricular complexes
  • Ventricular bigeminy
  • Ventricular escape complex
  • Ventricular escape rhythm on electrocardiogram
  • Ventricular extrasystoles with syncope, perodactyly and Robin sequence syndrome
  • Ventricular premature complex
  • Ventricular quadrigeminy
  • Ventricular trigeminy

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to I49.3: its own notes plus those printed at I49 and Chapter 9. A note printed at a category, block or chapter applies to every code under it.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From I49 Other cardiac arrhythmias applies to 12 codes
  • bradycardia NOS (R00.1)
  • neonatal dysrhythmia (P29.1-)
  • sinoatrial bradycardia (R00.1)
  • sinus bradycardia (R00.1)
  • vagal bradycardia (R00.1)
From Chapter 9 (I00-I99) Diseases of the circulatory system applies to 1,433 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Code First

The underlying condition named in the note is sequenced before this code.

From I49 Other cardiac arrhythmias applies to 12 codes
  • cardiac arrhythmia complicating:
  • abortion or ectopic or molar pregnancy (O00-O07, O08.8)
  • obstetric surgery and procedures (O75.4)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name I49.3, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming I49.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • R00 Abnormalities of heart beat
    specified arrhythmias (I47-I49) names I47-I49, which includes this code

Code Also 1

These codes say I49.3 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • M35.81 Multisystem inflammatory syndrome
    cardiac arrhythmia (I47-I49.-) names I47-I49, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR017
Cardiac dysrhythmias
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Arrhythmia

An arrhythmia is a problem with the rate or rhythm of your heartbeat. Your heart beats too quickly, too slowly, or with an irregular pattern. Changes in the electrical signals that control your heartbeat cause arrhythmias.

The full article covers:

  • What is an arrhythmia?
  • What causes an arrhythmia?
  • What are the symptoms of an arrhythmia?
  • How is an arrhythmia diagnosed?
  • What are the treatments for an arrhythmia?
  • Can arrhythmias be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I49.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
427.69 Premature beats NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About I49.3Overview

What is the ICD-10 code for ventricular premature depolarization?

The ICD-10-CM code for ventricular premature depolarization is I49.3 (sometimes written as I493). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is I49.3 (Other cardiac arrhythmias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report ventricular premature depolarization on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does I49.3 group to?

When ventricular premature depolarization is the principal diagnosis on an inpatient stay, it groups to MS-DRG 309, 310, 308, with relative weights from 0.5686 to 1.1809 depending on complications. Higher weights mean higher Medicare reimbursement.

What is coded first with I49.3?

The Code First note at I49, which applies to I49.3, reads: cardiac arrhythmia complicating: abortion or ectopic or molar pregnancy (O00-O07, O08.8); obstetric surgery and procedures (O75.4). When one of these applies, it is sequenced before I49.3.

What is the ICD-9 equivalent of I49.3?

Under the General Equivalence Mappings, ventricular premature depolarization converts to ICD-9-CM 427.69 (premature beats NEC). The mapping is approximate, so confirm the match fits the documentation.