2027 ICD-10-CM Diagnosis Code H35.389Toxic maculopathy, unspecified eye

ICD-10-CM Codes›H00–H59›H30-H36›H35

ICD-10-CM H35.389
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

H35.389 is a billable ICD-10-CM diagnosis code for toxic maculopathy, unspecified eye. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 124 through 125. Coders also document this condition as bilateral toxic maculopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Retinal and vitreous conditions.

Code Identity

ICD-10-CM Code
H35.389
Billable Status
Yes — Valid for Submission
Code Describes
Toxic maculopathy, unspecified eye
Short Description
Toxic maculopathy, unspecified eye
Same as the full description in the CMS dataset.
Parent Code
H35.38
Toxic maculopathy

Code Classification

ChapterH00–H59Diseases of the eye and adnexa
SectionH30-H36Disorders of choroid and retina
CategoryH35Other retinal disorders
This CodeH35.389Toxic maculopathy, unspecified eye

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral toxic maculopathy
  • Disorder of retina caused by pentosan polysulfate
  • Left toxic maculopathy
  • Pentosan polysulfate sodium maculopathy
  • Right toxic maculopathy
  • Toxic maculopathy
  • Toxic maculopathy of bilateral eyes caused by antimalarial drug

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to H35.389: its own notes plus those printed at H35.38, H35, and Chapter 7. A note printed at a category, block or chapter applies to every code under it.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From H35 Other retinal disorders applies to 175 codes
From Chapter 7 (H00-H59) Diseases of the eye and adnexa applies to 2,677 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury (trauma) of eye and orbit (S05.-)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • syphilis related eye disorders (A50.01, A50.3-, A51.43, A52.71)

Code First

The underlying condition named in the note is sequenced before this code.

From H35.38 Toxic maculopathy applies to 4 codes
  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From H35.38 Toxic maculopathy applies to 4 codes
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes

General instructions on how these codes are used.

From Chapter 7 (H00-H59) Diseases of the eye and adnexa applies to 2,677 codes
  • Use an external cause code following the code for the eye condition, if applicable, to identify the cause of the eye condition

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR EYE005
Retinal and vitreous conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Retinal Disorders

Retinal disorders are conditions that affect the retina, the thin light-sensitive tissue at the back of your eye. The retina senses light and sends signals to your brain so you can see.

The full article covers:

  • What are retinal disorders?
  • What causes retinal disorders?
  • What are common retinal disorders?
  • What are the symptoms of retinal disorders?
  • How are retinal disorders diagnosed?
  • How are retinal disorders treated?
  • Can retinal disorders be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert H35.389 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
362.55 Toxic maculopathy
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About H35.389Overview

What is the ICD-10 code for toxic maculopathy, unspecified eye?

The ICD-10-CM code for toxic maculopathy, unspecified eye is H35.389 (sometimes written as H35389). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is H35.389 (Toxic maculopathy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic maculopathy, unspecified eye on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does H35.389 group to?

When toxic maculopathy, unspecified eye is the principal diagnosis on an inpatient stay, it groups to MS-DRG 125, 124, with relative weights from 0.7699 to 1.2470 depending on complications. Higher weights mean higher Medicare reimbursement.

Does H35.389 need an additional code?

When the condition applies, yes. The Use Additional Code note at H35.38, which applies to H35.389, reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after H35.389.

What is the ICD-9 equivalent of H35.389?

Under the General Equivalence Mappings, toxic maculopathy, unspecified eye converts to ICD-9-CM 362.55 (toxic maculopathy). The mapping is approximate, so confirm the match fits the documentation.