2027 ICD-10-CM Diagnosis Code G72.3Periodic paralysis

ICD-10-CM Codes›G00–G99›G70-G73›G72

ICD-10-CM G72.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G72.3 is a billable ICD-10-CM diagnosis code for periodic paralysis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. Coders also document this condition as familial hyperkalemic periodic paralysis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Myopathies.

G72.3 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the ESRD (V21) category 75 for payment year 2027.

Code Identity

ICD-10-CM Code
G72.3
Billable Status
Yes — Valid for Submission
Code Describes
Periodic paralysis
Short Description
Periodic paralysis
Same as the full description in the CMS dataset.
Parent Code
Other and unspecified myopathies

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG70-G73Diseases of myoneural junction and muscle
CategoryG72Other and unspecified myopathies
This CodeG72.3Periodic paralysis

Medicare Risk Adjustment (HCC)Billing

G72.3 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
no payment category in the model that pays 100% of MA risk scores
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Other CMS Models
ESRD (V21): HCC 75
ESRD V21 weights: 0.059 dialysis, 0.284–0.323 functioning graft
Part D (RxHCC)
Not mapped
G72.3 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Familial hyperkalemic periodic paralysis
  • Familial hypokalemic periodic paralysis
  • Familial normokalemic periodic paralysis
  • Familial periodic paralysis
  • Periodic paralysis
  • Periodic paralysis with later-onset distal motor neuropathy
  • Periodic paralysis with transient compartment-like syndrome
  • Secondary periodic paralysis
  • Thyrotoxic periodic paralysis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G72.3: its own notes plus those printed at G72 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Familial periodic paralysis
  • Hyperkalemic periodic paralysis (familial)
  • Hypokalemic periodic paralysis (familial)
  • Myotonic periodic paralysis (familial)
  • Normokalemic paralysis (familial)
  • Potassium sensitive periodic paralysis

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On G72.3 itself
  • paramyotonia congenita (of von Eulenburg) (G71.19)
From G72 Other and unspecified myopathies applies to 9 codes
  • arthrogryposis multiplex congenita (Q74.3)
  • dermatopolymyositis (M33.-)
  • ischemic infarction of muscle (M62.2-)
  • myositis (M60.-)
  • polymyositis (M33.2.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G72.3, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming G72.3: they are not reported together with it, unless the two conditions are unrelated.

  • E87 Other disorders of fluid, electrolyte and acid-base balance
    familial periodic paralysis (G72.3)

Excludes2 1

These codes carry an Excludes2 note naming G72.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block M60-M63 Disorders of muscles
    muscular dystrophies and myopathies (G71-G72) names G71-G72, which includes this code

Code First 1

These codes say to code first a condition named in the note, and G72.3 is one of the conditions named.

  • M62.84 Sarcopenia
    other and unspecified myopathies (G72.-) names G72.-, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS018
Myopathies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Paralysis, Hyperkalemic Periodic

    an autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. during attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. episodes last from 15-60 minutes and typically occur after a period of rest following exercise. a defect in skeletal muscle sodium channels has been identified as the cause of this condition. normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (adams et al., principles of neurology, 6th ed, p1481)

Patient EducationClinical

Paralysis

Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles. Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also occur in just one area, or it can be widespread.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G72.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
359.3 Periodic paralysis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G72.3Overview

What is the ICD-10 code for periodic paralysis?

The ICD-10-CM code for periodic paralysis is G72.3 (sometimes written as G723). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G72.3 (Other and unspecified myopathies) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report periodic paralysis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G72.3 group to?

When periodic paralysis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Can G72.3 be reported with G71.19?

Not as a rule. The Excludes1 note on G72.3 lists "paramyotonia congenita (of von Eulenburg) (G71.19)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of G72.3?

Under the General Equivalence Mappings, periodic paralysis converts to ICD-9-CM 359.3 (periodic paralysis). The mapping is a direct match.

Does G72.3 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage: G72.3 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the ESRD (V21) category 75 (Polyneuropathy).