2027 ICD-10-CM Diagnosis Code G61.81Chronic inflammatory demyelinating polyneuritis

ICD-10-CM Codes›G00–G99›G60-G65›G61

ICD-10-CM G61.81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G61.81 is a billable ICD-10-CM diagnosis code for chronic inflammatory demyelinating polyneuritis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 73 through 74. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 108 closely related codes. Coders also document this condition as autoimmune brachial neuritis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Polyneuropathies.

For Medicare Advantage risk adjustment, G61.81 maps to CMS-HCC Category 193 (Chronic Inflammatory Demyelinating Polyneuritis and Multifocal Motor Neuropathy) under the V28 model, adding a risk factor of about 1.692 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
G61.81
Billable Status
Yes — Valid for Submission
Code Describes
Chronic inflammatory demyelinating polyneuritis
Short Description
Chronic inflammatory demyelinating polyneuritis
Same as the full description in the CMS dataset.
Parent Code
Other inflammatory polyneuropathies

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG60-G65Polyneuropathies and other disorders of the peripheral nervous system
CategoryG61Inflammatory polyneuropathy
This CodeG61.81Chronic inflammatory demyelinating polyneuritis

Medicare Risk Adjustment (HCC)Billing

G61.81 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 193— Chronic Inflammatory Demyelinating Polyneuritis and Multifocal Motor Neuropathy
Payment HCC · PY 2027 one of 2 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+1.692
community, non-dual, aged · ranges 0.850–1.692 across segments
Hierarchy
Top of its hierarchy
HCC 193 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 75
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 75 · ESRD (V21): HCC 75 · ESRD (V24): HCC 75
ESRD V21 weights: 0.059 dialysis, 0.284–0.323 functioning graft · ESRD V24 weights: 0.074 dialysis, 0.344–0.599 functioning graft
Part D (RxHCC)
RxHCC 157 — Chronic Inflammatory Demyelinating Polyneuritis
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Autoimmune brachial neuritis
  • Autoimmune neuritis of nerve root and/or plexus
  • Brachial variant of chronic immune demyelinating polyradiculoneuropathy
  • CANOMAD syndrome
  • Chronic inflammatory demyelinating disease of peripheral nervous system and central nervous system
  • Chronic inflammatory demyelinating polyradiculoneuropathy
  • Chronic inflammatory demyelinating polyradiculoneuropathy with central nervous system demyelination
  • Demyelinating sensorimotor neuropathy
  • Idiopathic chronic neuropathy
  • Polyneuropathy associated with monoclonal immunoglobulin M antibodies to myelin-associated glycoprotein

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G61.81: its own notes plus those printed at block G60-G65 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block G60-G65 Polyneuropathies and other disorders of the peripheral nervous system applies to 24 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS015
Polyneuropathies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

    a slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. the course may be relapsing-remitting or demonstrate a step-wise progression. protein is usually elevated in the spinal fluid and cranial nerves are typically spared. guillain-barre syndrome features a relatively rapid progression of disease which distinguishes it from this condition. (adams et al., principles of neurology, 6th ed, p1337)

Patient EducationClinical

Peripheral Nerve Disorders

Nerves are like wires that carry messages back and forth between your brain and your body. Your peripheral nerves branch off from your brain and spinal cord and connect to all parts of your body, including your muscles and organs.

The full article covers:

  • What are peripheral nerves?
  • What are peripheral nerve disorders?
  • What causes peripheral nerve disorders?
  • What are the symptoms of peripheral nerve disorders?
  • How are peripheral nerve disorders diagnosed?
  • What are the treatments for peripheral nerve disorders?
  • Can peripheral nerve disorders be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G61.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
357.81 Chr inflam polyneuritis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G61.81Overview

What is the ICD-10 code for chronic inflammatory demyelinating polyneuritis?

The ICD-10-CM code for chronic inflammatory demyelinating polyneuritis is G61.81 (sometimes written as G6181). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G61.81 (Other inflammatory polyneuropathies) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report chronic inflammatory demyelinating polyneuritis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G61.81 group to?

When chronic inflammatory demyelinating polyneuritis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 74, 73, with relative weights from 1.0172 to 1.5773 depending on complications. Higher weights mean higher Medicare reimbursement.

Is G61.81 a CC or MCC?

CMS lists G61.81 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 108 closely related codes in its exclusion list.

Can G61.81 be reported with M79.2?

Not as a rule. The Excludes1 note at block G60-G65, which applies to G61.81, lists "neuralgia NOS (M79.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is G61.81?

G61.81 (chronic inflammatory demyelinating polyneuritis) maps to CMS-HCC Category 193 (Chronic Inflammatory Demyelinating Polyneuritis and Multifocal Motor Neuropathy), commonly written as HCC 193, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 75 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 157.

Does G61.81 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, G61.81 adds a risk adjustment factor of about 1.692 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.850 to 1.692 depending on the payment segment). HCC 193 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 193 category page.