2027 ICD-10-CM Diagnosis Code G25.82Stiff-man syndrome

ICD-10-CM Codes›G00–G99›G20-G26›G25

ICD-10-CM G25.82
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G25.82 is a billable ICD-10-CM diagnosis code for stiff-man syndrome. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 95 closely related codes. Coders also document this condition as disorders of spinal neurones manifest by hyperactivity. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (often hereditary or degenerative).

Code Identity

ICD-10-CM Code
G25.82
Billable Status
Yes — Valid for Submission
Code Describes
Stiff-man syndrome
Short Description
Stiff-man syndrome
Same as the full description in the CMS dataset.
Parent Code
G25.8
Other specified extrapyramidal and movement disorders

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG20-G26Extrapyramidal and movement disorders
CategoryG25Other extrapyramidal and movement disorders
This CodeG25.82Stiff-man syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Disorders of spinal neurones manifest by hyperactivity
  • Stiff-person syndrome

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G25.82: its own notes plus those printed at G25 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From G25 Other extrapyramidal and movement disorders applies to 16 codes
  • sleep related movement disorders (G47.6-)
From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G25.82, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming G25.82: they are not reported together with it, unless the two conditions are unrelated.

  • M62 Other disorders of muscle
    stiff-man syndrome (G25.82)
  • R25 Abnormal involuntary movements
    specific movement disorders (G20-G26) names G20-G26, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming G25.82: its condition is not part of those codes, and both may be reported when the patient has both.

  • F98.4 Stereotyped movement disorders
    movement disorders of organic origin (G20-G25) names G20-G25, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS006
Other nervous system disorders (often hereditary or degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Stiff-Person Syndrome

    a condition characterized by persistent spasms (spasm) involving multiple muscles, primarily in the lower limbs and trunk. the illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. minor sensory stimuli, such as noise and light touch, precipitate severe spasms. spasms do not occur during sleep and only rarely involve cranial muscles. respiration may become impaired in advanced cases. (adams et al., principles of neurology, 6th ed, p1492; neurology 1998 jul;51(1):85-93)

Patient EducationClinical

Autoimmune Diseases

Your immune system protects you from disease and infection by attacking germs that get into your body, such as viruses and bacteria. Your immune system can tell that the germs aren't part of you, so it destroys them. If you have an autoimmune disease, your immune system attacks the healthy cells of your organs and tissues by mistake.

The full article covers:

  • What are autoimmune diseases?
  • What causes autoimmune diseases?
  • Who is at risk for autoimmune diseases?
  • What are the symptoms of autoimmune diseases?
  • How are autoimmune diseases diagnosed?
  • What are the treatments for autoimmune diseases?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G25.82 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
333.91 Stiff-man syndrome
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G25.82Overview

What is the ICD-10 code for stiff-man syndrome?

The ICD-10-CM code for stiff-man syndrome is G25.82 (sometimes written as G2582). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G25.82 (Other specified extrapyramidal and movement disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report stiff-man syndrome on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G25.82 group to?

When stiff-man syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Is G25.82 a CC or MCC?

CMS lists G25.82 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 95 closely related codes in its exclusion list.

What is the ICD-9 equivalent of G25.82?

Under the General Equivalence Mappings, stiff-man syndrome converts to ICD-9-CM 333.91 (stiff-man syndrome). The mapping is a direct match.