2026 ICD-10-CM Diagnosis Code E50.4Vitamin A deficiency with keratomalacia

ICD-10-CM Codes›E00–E89›E50-E64›E50

ICD-10-CM E50.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E50.4 is a billable ICD-10-CM diagnosis code for vitamin A deficiency with keratomalacia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 124 through 125. Coders also document this condition as keratomalacia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional deficiencies.

Code Identity

ICD-10-CM Code
E50.4
Billable Status
Yes — Valid for Submission
Code Describes
Vitamin A deficiency with keratomalacia
Short Description
Vitamin A deficiency with keratomalacia
Same as the full description in the CMS dataset.
Parent Code
E50
Vitamin A deficiency

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE50Vitamin A deficiency
This CodeE50.4Vitamin A deficiency with keratomalacia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Keratomalacia
  • Vitamin A deficiency with keratomalacia
  • Xerophthalmia

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • vitamin (multiple) NOS
        • A
          • with
            • keratomalacia
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • xerotic
        • vitamin A deficiency
    • Keratomalacia
      • vitamin A deficiency

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END007
Nutritional deficiencies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Xerophthalmia

    dryness of the eye surfaces caused by deficiency of tears or conjunctival secretions. it may be associated with vitamin a deficiency, trauma, or any condition in which the eyelids do not close completely.

Patient EducationClinical

Malnutrition

Malnutrition means that your body isn't getting enough calories or the right balance of nutrients to stay healthy. This can happen if you don't get enough protein, carbohydrates, and fats, eat too much unhealthy food, or don't get the vitamins and minerals your body needs.

The full article covers:

  • What is malnutrition?
  • What are the types of malnutrition?
  • What causes malnutrition?
  • Who is at risk for developing malnutrition?
  • What are the symptoms of malnutrition?
  • How is malnutrition diagnosed?
  • What are the treatments for malnutrition?
  • Can malnutrition be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E50.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
264.4 Vit A keratomalacia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E50.4Overview

Is E50.4 (Vitamin A deficiency) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report vitamin A deficiency with keratomalacia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E50.4 group to?

When vitamin A deficiency with keratomalacia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 124, 125, with relative weights from 0.7678 to 1.3231 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E50.4?

Under the General Equivalence Mappings, vitamin A deficiency with keratomalacia converts to ICD-9-CM 264.4 (vit A keratomalacia). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.