2026 ICD-10-CM Diagnosis Code E04.0Nontoxic diffuse goiter

ICD-10-CM Codes›E00–E89›E00-E07›E04

ICD-10-CM E04.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E04.0 is a billable ICD-10-CM diagnosis code for nontoxic diffuse goiter. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. Coders also document this condition as colloid goiter. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Thyroid disorders.

Code Identity

ICD-10-CM Code
E04.0
Billable Status
Yes — Valid for Submission
Code Describes
Nontoxic diffuse goiter
Short Description
Nontoxic diffuse goiter
Same as the full description in the CMS dataset.
Parent Code
E04
Other nontoxic goiter

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE04Other nontoxic goiter
This CodeE04.0Nontoxic diffuse goiter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Colloid goiter
  • Diffuse goiter
  • Diffuse thyroid goiter without thyrotoxicosis
  • Simple goiter

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Diffuse (colloid) nontoxic goiter
  • Simple nontoxic goiter

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Bronchocele meaning goiter
    • Goiter(plunging) (substernal)
      • nontoxic
        • diffuse (colloid)
    • Goiter(plunging) (substernal)
      • nontoxic
        • simple
    • Goiter(plunging) (substernal)
      • simple

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END001
Thyroid disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Congenital Hypothyroidism with Diffuse Goiter|Congenital hypothyroidism with diffuse goiter

    evidence of congenital hypothyroidism with diffuse goiter.

  • Diffuse Goiter

    enlargement of the entire thyroid gland without discrete mass(es).

  • Non-Toxic Diffuse Goiter|Nontoxic diffuse goiter

    a diffuse goiter that is not associated with changes in thyroid function or malignancy.

  • Thyrotoxicosis with Diffuse Goiter with Thyrotoxic Crisis or Storm|Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

    evidence of thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm.

  • Thyrotoxicosis with Diffuse Goiter without Thyrotoxic Crisis|Thyrotoxicosis with diffuse goiter without thyrotoxic crisis

    evidence of thyrotoxicosis with diffuse goiter without thyrotoxic crisis.

Patient EducationClinical

Thyroid Diseases

Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E04.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
240.0 Simple goiter
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E04.0Overview

Is E04.0 (Other nontoxic goiter) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report nontoxic diffuse goiter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E04.0 group to?

When nontoxic diffuse goiter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E04.0?

Under the General Equivalence Mappings, nontoxic diffuse goiter converts to ICD-9-CM 240.0 (simple goiter). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.