2027 ICD-10-CM Diagnosis Code E05Thyrotoxicosis [hyperthyroidism]

ICD-10-CM Codes›E00–E89›E00-E07›E05

ICD-10-CM E05
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E05 is a non-billable ICD-10-CM category code for thyrotoxicosis [hyperthyroidism], so it cannot be submitted on claims. Use a more specific code from this category instead, such as E05.00, E05.01, E05.10, and E05.11.

Code Identity

ICD-10-CM Code
E05
Billable Status
No — Non-Billable Category
Code Describes
Thyrotoxicosis [hyperthyroidism]
Short Description
Thyrotoxicosis [hyperthyroidism]
Same as the full description in the CMS dataset.
Chapter
E00-E07
Disorders of thyroid gland

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE05Thyrotoxicosis [hyperthyroidism]
This CodeE05Thyrotoxicosis [hyperthyroidism]

Specific Coding for Thyrotoxicosis [hyperthyroidism]Overview

Non-specific codes like E05 require more characters. Use one of these billable codes instead:

  • E05.0 for Thyrotoxicosis with diffuse goiter

  • Use E05.00 for Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm

  • Use E05.01 for Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

  • E05.1 for Thyrotoxicosis with toxic single thyroid nodule

  • Use E05.10 for Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm

  • Use E05.11 for Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm

  • E05.2 for Thyrotoxicosis with toxic multinodular goiter

  • Use E05.20 for Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm

  • Use E05.21 for Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm

  • E05.3 for Thyrotoxicosis from ectopic thyroid tissue

  • Use E05.30 for Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis or storm

  • Use E05.31 for Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis or storm

  • E05.4 for Thyrotoxicosis factitia

  • Use E05.40 for Thyrotoxicosis factitia without thyrotoxic crisis or storm

  • Use E05.41 for Thyrotoxicosis factitia with thyrotoxic crisis or storm

  • E05.8 for Other thyrotoxicosis

  • Use E05.80 for Other thyrotoxicosis without thyrotoxic crisis or storm

  • Use E05.81 for Other thyrotoxicosis with thyrotoxic crisis or storm

  • E05.9 for Thyrotoxicosis, unspecified

  • Use E05.90 for Thyrotoxicosis, unspecified without thyrotoxic crisis or storm

  • Use E05.91 for Thyrotoxicosis, unspecified with thyrotoxic crisis or storm

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E05: its own notes plus those printed at Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E05 itself
  • chronic thyroiditis with transient thyrotoxicosis (E06.2)
  • neonatal thyrotoxicosis (P72.1)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E05, its category, or a range that includes it.

Applicable To 1

These notes mention E05.

  • Z83.4 Family history of other endocrine, nutritional and metabolic diseases
    Conditions classifiable to E00-E07, E15-E88 names E00-E07, which includes this code

Code First 4

These codes say to code first a condition named in the note, and E05 is one of the conditions named.

  • G73.3 Myasthenic syndromes in other diseases classified elsewhere
    thyrotoxicosis (E05.-)
  • G99.0 Autonomic neuropathy in diseases classified elsewhere
    hyperthyroidism (E05.-)
  • M14.8 Arthropathies in other specified diseases classified elsewhere
    thyrotoxicosis [hyperthyroidism] (E05.-)
  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E00-E07, which includes this code

Code Also 1

These codes say E05 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • I27.29 Other secondary pulmonary hypertension
    hyperthyroidism (E05.-)

Patient EducationClinical

Hyperthyroidism

Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs.

The full article covers:

  • What is hyperthyroidism?
  • What causes hyperthyroidism?
  • Who is at risk for hyperthyroidism?
  • What are the symptoms of hyperthyroidism?
  • What other problems can hyperthyroidism cause?
  • How is hyperthyroidism diagnosed?
  • What are the treatments for hyperthyroidism?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E05Overview

What is the ICD-10 code for thyrotoxicosis [hyperthyroidism]?

E05 is the ICD-10-CM category for thyrotoxicosis [hyperthyroidism], but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E05 (Thyrotoxicosis [hyperthyroidism]) a billable code?

No. This is a category header that groups the codes for thyrotoxicosis [hyperthyroidism], and headers cannot be submitted on claims. Claims for thyrotoxicosis [hyperthyroidism] need a more specific code from this category, such as E05.00, E05.01, and E05.10.

Can E05 be reported with E06.2?

Not as a rule. The Excludes1 note on E05 lists "chronic thyroiditis with transient thyrotoxicosis (E06.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).