ICD-10-CM Code E05

Thyrotoxicosis [hyperthyroidism]

Version 2021 Non-Billable Code

Not Valid for Submission

E05 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of thyrotoxicosis [hyperthyroidism]. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions.

ICD-10:E05
Short Description:Thyrotoxicosis [hyperthyroidism]
Long Description:Thyrotoxicosis [hyperthyroidism]

Consider the following ICD-10 codes with a higher level of specificity:

  • E05.0 - Thyrotoxicosis with diffuse goiter
  • E05.00 - Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
  • E05.01 - Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm
  • E05.1 - Thyrotoxicosis with toxic single thyroid nodule
  • E05.10 - Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
  • E05.11 - Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
  • E05.2 - Thyrotoxicosis with toxic multinodular goiter
  • E05.20 - Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
  • E05.21 - Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
  • E05.3 - Thyrotoxicosis from ectopic thyroid tissue
  • E05.30 - Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis or storm
  • E05.31 - Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis or storm
  • E05.4 - Thyrotoxicosis factitia
  • E05.40 - Thyrotoxicosis factitia without thyrotoxic crisis or storm
  • E05.41 - Thyrotoxicosis factitia with thyrotoxic crisis or storm
  • E05.8 - Other thyrotoxicosis
  • E05.80 - Other thyrotoxicosis without thyrotoxic crisis or storm
  • E05.81 - Other thyrotoxicosis with thyrotoxic crisis or storm
  • E05.9 - Thyrotoxicosis, unspecified
  • E05.90 - Thyrotoxicosis, unspecified without thyrotoxic crisis or storm
  • E05.91 - Thyrotoxicosis, unspecified with thyrotoxic crisis or storm

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E05:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • chronic thyroiditis with transient thyrotoxicosis E06.2
  • neonatal thyrotoxicosis P72.1

Clinical Information

  • THYROTOXICOSIS-. a hypermetabolic syndrome caused by excess thyroid hormones which may come from endogenous or exogenous sources. the endogenous source of hormone may be thyroid hyperplasia; thyroid neoplasms; or hormone producing extrathyroidal tissue. thyrotoxicosis is characterized by nervousness; tachycardia; fatigue; weight loss; heat intolerance; and excessive sweating.

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of thyroid gland (E00-E07)
      • Thyrotoxicosis [hyperthyroidism] (E05)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Hyperthyroidism

Your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. It is one of your endocrine glands, which make hormones. Thyroid hormones control the rate of many activities in your body. These include how fast you burn calories and how fast your heart beats. All of these activities are your body's metabolism. If your thyroid is too active, it makes more thyroid hormones than your body needs. This is called hyperthyroidism.

Hyperthyroidism is more common in women, people with other thyroid problems, and those over 60 years old. Graves' disease, an autoimmune disorder, is the most common cause. Other causes include thyroid nodules, thyroiditis, consuming too much iodine, and taking too much synthetic thyroid hormone.

The symptoms can vary from person to person. They may include

  • Being nervous or irritable
  • Mood swings
  • Fatigue or muscle weakness
  • Heat intolerance
  • Trouble sleeping
  • Hand tremors
  • Rapid and irregular heartbeat
  • Frequent bowel movements or diarrhea
  • Weight loss
  • Goiter, which is an enlarged thyroid that may cause the neck to look swollen

To diagnose hyperthyroidism, your doctor will do a physical exam, look at your symptoms, and do thyroid tests. Treatment is with medicines, radioiodine therapy, or thyroid surgery. No single treatment works for everyone.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

  • Eyes - bulging (Medical Encyclopedia)
  • Factitious hyperthyroidism (Medical Encyclopedia)
  • Graves disease (Medical Encyclopedia)
  • Hyperthyroidism (Medical Encyclopedia)
  • Radioactive iodine uptake (Medical Encyclopedia)
  • Silent thyroiditis (Medical Encyclopedia)
  • Subacute thyroiditis (Medical Encyclopedia)
  • T3 test (Medical Encyclopedia)
  • T4 test (Medical Encyclopedia)
  • Thyroid Tests - NIH (National Institute of Diabetes and Digestive and Kidney Diseases)
  • Thyrotoxic periodic paralysis (Medical Encyclopedia)
  • TSH test (Medical Encyclopedia)
  • TSI (Medical Encyclopedia)

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