2021 ICD-10-CM Code D81.2
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
Valid for Submission
D81.2 is a billable diagnosis code used to specify a medical diagnosis of severe combined immunodeficiency [scid] with low or normal b-cell numbers. The code D81.2 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D81.2 might also be used to specify conditions or terms like severe combined immunodeficiency with low or normal b-cell numbers or t cell negative b cell positive severe combined immunodeficiency due to gamma chain deficiency.
| ICD-10: | D81.2 |
| Short Description: | Severe combined immunodef w low or normal B-cell numbers |
| Long Description: | Severe combined immunodeficiency [SCID] with low or normal B-cell numbers |
Code Classification
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D81.2 are found in the index:
- - Immunodeficiency - D84.9
- - combined - D81.9
- - severe (SCID) - D81.9
- - with
- - low or normal B-cell numbers - D81.2
- - with
- - severe (SCID) - D81.9
- - combined - D81.9
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Severe combined immunodeficiency with low or normal B-cell numbers
- T cell negative B cell positive severe combined immunodeficiency due to gamma chain deficiency
Diagnostic Related Groups - MS-DRG Mapping
The ICD-10 code D81.2 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2020 through 09/30/2021.
- 808 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC - Relative Weight: 2.1779
- 809 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC - Relative Weight: 1.2217
- 810 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC - Relative Weight: 0.9607
Convert D81.2 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D81.2 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
- 279.2 - Combined immunity defic (Approximate Flag)
Information for Patients
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.
If your immune system cannot do its job, the results can be serious. Disorders of the immune system include
- Allergy and asthma - immune responses to substances that are usually not harmful
- Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
- Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake
NIH: National Institute of Allergy and Infectious Diseases
- Agammaglobulinemia (Medical Encyclopedia)
- Aging changes in immunity (Medical Encyclopedia)
- Chronic granulomatous disease (Medical Encyclopedia)
- Graft-versus-host disease (Medical Encyclopedia)
- Histiocytosis (Medical Encyclopedia)
- Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
- Immune response (Medical Encyclopedia)
- Immunodeficiency disorders (Medical Encyclopedia)
- Selective deficiency of IgA (Medical Encyclopedia)
[Learn More]
Omenn syndrome Omenn syndrome is an inherited disorder of the immune system (immunodeficiency). Omenn syndrome is one of several forms of severe combined immunodeficiency (SCID), a group of disorders that cause individuals to have virtually no immune protection from bacteria, viruses, and fungi. Individuals with SCID are prone to repeated and persistent infections that can be very serious or life-threatening. Infants with Omenn syndrome typically experience pneumonia and chronic diarrhea. Often the organisms that cause infection in people with this disorder are described as opportunistic because they ordinarily do not cause illness in healthy people.In addition to immunodeficiency, children with Omenn syndrome develop autoimmunity, in which the immune system attacks the body's own tissues and organs. This abnormal immune reaction can cause very red skin (erythroderma), hair loss (alopecia), and an enlarged liver and spleen (hepatosplenomegaly). In addition, affected individuals have enlargement of tissues that produce infection-fighting white blood cells called lymphocytes. These include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body.If not treated in a way that restores immune function, children with Omenn syndrome usually survive only until age 1 or 2.
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Code History
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)