2026 ICD-10-CM Diagnosis Code D47.2Monoclonal gammopathy

ICD-10-CM Codes›C00–D49›D37-D48›D47

ICD-10-CM D47.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D47.2 is a billable ICD-10-CM diagnosis code for monoclonal gammopathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D47.2
Billable Status
Yes — Valid for Submission
Code Describes
Monoclonal gammopathy
Short Description
Monoclonal gammopathy
Same as the full description in the CMS dataset.
Parent Code
D47
Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD47Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
This CodeD47.2Monoclonal gammopathy

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign monoclonal gammopathy
  • Biclonal gammopathy
  • Castleman disease
  • Castleman disease with immunoglobulin M monoclonal gammopathy of uncertain significance
  • Chronic urticaria
  • Complex multigenic autoinflammatory syndrome
  • Dysgammaglobulinemia
  • Gammopathy
  • Hyperplastic lymph node
  • Hypersensitivity reaction mediated by immune complex
  • Hypogammaglobulinemia
  • Hypogammaglobulinemia due to monoclonal gammopathy of undetermined significance
  • IgA monoclonal gammopathy of uncertain significance
  • IgD monoclonal gammopathy of uncertain significance
  • IgG monoclonal gammopathy of uncertain significance
  • IgM monoclonal gammopathy of uncertain significance
  • Immunoglobulin G deficiency
  • Immunoglobulin G deficiency due to monoclonal gammopathy of undetermined significance
  • Immunosecretory disorder
  • Light chain disease
  • Light chain monoclonal gammopathy of uncertain significance
  • Monoclonal free light chain detected
  • Monoclonal gammopathy
  • Monoclonal gammopathy of uncertain significance
  • Monoclonal immunoglobulin A detected
  • Monoclonal immunoglobulin D detected
  • Monoclonal immunoglobulin G detected
  • Motor neuron disease due to gammopathy
  • Necrotizing cutaneous vasculitis
  • Neuropathy associated with dysproteinemias
  • Neuropathy in benign monoclonal gammopathy
  • Non-amyloid monoclonal immunoglobulin deposition disease
  • POEMS syndrome
  • Schnitzler syndrome
  • TEMPI syndrome
  • Triclonal gammopathy
  • Urticarial vasculitis
  • Urticarial vasculitis with monoclonal IgM component, Schnitzler

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Monoclonal gammopathy of undetermined significance MGUS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Gammopathy(of undetermined significance [MGUS])
    • Gammopathy(of undetermined significance [MGUS])
      • associated with lymphoplasmacytic dyscrasia
    • Gammopathy(of undetermined significance [MGUS])
      • monoclonal
    • Macroglobulinemia(idiopathic) (primary)
      • monoclonal (essential)
    • Paraproteinemia
      • monoclonal
    • Paraproteinemia
      • secondary to malignant disease
    • Syndrome
      • Schnitzler

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Dysgammaglobulinemia

    an immunologic deficiency state characterized by selective deficiencies of one or more, but not all, classes of immunoglobulins.

  • Castleman Disease

    large benign, hyperplastic lymph nodes. the more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. plasma cells are often present and represent another subtype with the plasma cells containing igm and immunoglobulin a.

  • Schnitzler Syndrome

    an extremely rare condition manifested as monoclonal immunoglobulin m dysproteinemia without features of lymphoproliferative disease, but with chronic urticaria, fever of unknown origin, disabling bone pain, hyperostosis, and increased erythrocyte sedimentation rate.

  • Chronic Urticaria

    wheals (urticaria) and/or angioedema presented with daily symptoms lasting for more than 6 weeks. it may be classified into chronic spontaneous and chronic inducible urticaria depending on whether a specific trigger can be linked to the development of vascular reaction.

  • POEMS Syndrome

    a multisystemic disorder characterized by a sensorimotor polyneuropathy (polyneuropathies), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. other clinical features which may be present include edema; cachexia; microangiopathic glomerulopathy; pulmonary hypertension (hypertension, pulmonary); cutaneous necrosis; thrombocytosis; and polycythemia. this disorder is frequently associated with osteosclerotic myeloma. (from adams et al., principles of neurology, 6th ed, p1335; rev med interne 1997;18(7):553-62)

  • Biclonal Gammopathy

    a primary disturbance in immunoglobulin synthesis characterized by the presence of two distinct monoclonal immunoglobulins in the serum or urine.

  • TEMPI Syndrome

    a rare syndrome characterized by telangiectasias, elevated erythropoietin level and erythrocytosis, monoclonal gammopathy, perinephric fluid collections, and intrapulmonary shunting. it is best classified as a type of plasma cell dyscrasia with paraneoplastic manifestations.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D47.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
273.1 Monoclon paraproteinemia
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D47.2Overview

Is D47.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report monoclonal gammopathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D47.2 group to?

When monoclonal gammopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D47.2?

Under the General Equivalence Mappings, monoclonal gammopathy converts to ICD-9-CM 273.1 (monoclon paraproteinemia). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.