2026 ICD-10-CM Diagnosis Code D21.21Benign neoplasm of connective and other soft tissue of right lower limb, including hip

ICD-10-CM Codes›C00–D49›D10-D36›D21

ICD-10-CM D21.21
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D21.21 is a billable ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of right lower limb, including hip. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. Coders also document this condition as benign neoplasm of soft tissues of right lower limb. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D21.21
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of connective and other soft tissue of right lower limb, including hip
Short Description
Ben neoplm of connctv/soft tiss of right lower limb, inc hip
Parent Code
D21.2
Benign neoplasm of connective and other soft tissue of lower limb, including hip

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD21Other benign neoplasms of connective and other soft tissue
This CodeD21.21Benign neoplasm of connective and other soft tissue of right lower limb, including hip

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign neoplasm of soft tissues of right lower limb
  • Bilateral benign neoplasm of soft tissue of lower limbs

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
aponeurosis › plantarC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › ankleC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › calfC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › extremity › lowerC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › footC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › heelC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › hipC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › kneeC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › legC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › limb NEC › lowerC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › popliteal fossa or spaceC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › thighC49.2C79.89–D21.2D48.1D49.2
connective tissue NEC › toeC49.2C79.89–D21.2D48.1D49.2
fascia [See Also: Neoplasm, connective tissue] › plantarC49.2C79.89–D21.2D48.1D49.2

Patient EducationClinical

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D21.21 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
215.3 Ben neo soft tissue leg
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D21.21Overview

Is D21.21 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of connective and other soft tissue of right lower limb, including hip on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D21.21 group to?

When benign neoplasm of connective and other soft tissue of right lower limb, including hip is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D21.21?

Under the General Equivalence Mappings, benign neoplasm of connective and other soft tissue of right lower limb, including hip converts to ICD-9-CM 215.3 (ben neo soft tissue leg). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.