2026 ICD-10-CM Diagnosis Code A52.2Asymptomatic neurosyphilis

ICD-10-CM Codes›A00–B99›A50-A64›A52

ICD-10-CM A52.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A52.2 is a billable ICD-10-CM diagnosis code for asymptomatic neurosyphilis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified CNS infection and poliomyelitis and Sexually transmitted infections (excluding HIV and hepatitis).

Code Identity

ICD-10-CM Code
A52.2
Billable Status
Yes — Valid for Submission
Code Describes
Asymptomatic neurosyphilis
Short Description
Asymptomatic neurosyphilis
Same as the full description in the CMS dataset.
Parent Code
A52
Late syphilis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA52Late syphilis
This CodeA52.2Asymptomatic neurosyphilis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Asymptomatic neurosyphilis
  • Asymptomatic secondary neurosyphilis
  • Late quaternary neurosyphilis
  • Secondary neurosyphilis
  • Secondary syphilis of nervous system

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Neurosyphilis(arrested) (early) (gumma) (late) (latent) (recurrent) (relapse)
      • asymptomatic
    • Neurosyphilis(arrested) (early) (gumma) (late) (latent) (recurrent) (relapse)
      • serological (without symptoms)
    • Syphilis, syphilitic(acquired)
      • latent
        • central nervous system

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS003
Other specified CNS infection and poliomyelitis
Default principal diagnosis: inpatient No · outpatient No
CCSR INF010
Sexually transmitted infections (excluding HIV and hepatitis)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Syphilis

Syphilis is a sexually transmitted infection (STI) caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A52.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
094.3 Asymptomat neurosyphilis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A52.2Overview

Is A52.2 (Late syphilis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report asymptomatic neurosyphilis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of A52.2?

Under the General Equivalence Mappings, asymptomatic neurosyphilis converts to ICD-9-CM 094.3 (asymptomat neurosyphilis). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.