ICD-10 Diagnosis Code E85.4

Organ-limited amyloidosis

Diagnosis Code E85.4

ICD-10: E85.4
Short Description: Organ-limited amyloidosis
Long Description: Organ-limited amyloidosis
This is the 2018 version of the ICD-10-CM diagnosis code E85.4

Valid for Submission
The code E85.4 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Amyloidosis (E85)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code E85.4 is grouped in the following Diagnostic Related Group(s) (MS-DRG V34.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Acquired macroglossia
  • AD type amyloidosis
  • Age-related amyloidosis
  • Age-related amyloidosis
  • Amyloid disease of the urethra
  • Amyloid myopathy
  • Amyloid of bladder
  • Amyloid of cornea
  • Amyloid of prostate
  • Amyloid of testes
  • Amyloid of ureter
  • Amyloid of vitreous
  • Amyloidosis limited to skin
  • Amyloidosis of skin
  • Amyloidosis of spleen
  • Arthritis secondary to amyloidosis
  • Autonomic neuropathy due to amyloid
  • Beta-2 microglobulin arthropathy
  • Bullous cutaneous amyloidosis
  • Cerebral amyloid angiopathy
  • Cerebrovascular amyloidosis
  • Conjunctival amyloidosis
  • Cutaneous amyloidosis
  • Danish type familial amyloid cardiomyopathy
  • Dominant primary localized cutaneous amyloidosis
  • Enlargement of tongue
  • Familial amyloid polyneuropathy with cutaneous amyloidosis
  • Familial cardiomyopathy
  • Familial non-neuropathic amyloidosis
  • Gingival amyloidosis
  • Hepatic amyloidosis
  • Hereditary cerebral amyloid angiopathy, Dutch type
  • Hereditary oculoleptomeningeal amyloid angiopathy
  • Heredofamilial systemic amyloidosis affecting skin
  • Isolated atrial amyloid
  • Isolated corneal amyloidosis
  • Laryngeal amyloidosis
  • Localized amyloid deposit
  • Localized amyloidosis
  • Localized hereditary amyloidosis
  • Localized hereditary amyloidosis
  • Localized non-hereditary amyloidosis
  • Macroglossia due to amyloidosis
  • Macular cutaneous amyloidosis
  • Maculopapular amyloidosis
  • Neuropathy associated with dysproteinemias
  • Neuropathy in secondary amyloidosis
  • Nodular amyloidosis
  • Ocular amyloid deposit
  • Papular cutaneous amyloid
  • Poikilodermal cutaneous amyloid
  • Pulmonary amyloidosis
  • Secondary localized cutaneous amyloidosis
  • Senile brain amyloidosis
  • Senile cardiac amyloidosis
  • Sporadic cerebral amyloid angiopathy
  • Systemic amyloidosis affecting skin
  • Ureteritis

Index of Diseases and Injuries
References found for the code E85.4 in the Index of Diseases and Injuries:

Information for Patients


Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

  • Primary - with no known cause
  • Secondary - caused by another disease, including some types of cancer
  • Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.

  • Cardiac amyloidosis (Medical Encyclopedia)
  • Hereditary amyloidosis (Medical Encyclopedia)
  • Primary amyloidosis (Medical Encyclopedia)
  • Secondary systemic amyloidosis (Medical Encyclopedia)

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