2026 ICD-10-CM Diagnosis Code Z92.86Personal history of gene therapy

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z92

ICD-10-CM Z92.86
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z92.86 is a billable ICD-10-CM diagnosis code for personal history of gene therapy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as history of gene therapy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Personal history of other disease.

Code Identity

ICD-10-CM Code
Z92.86
Billable Status
Yes — Valid for Submission
Code Describes
Personal history of gene therapy
Short Description
Personal history of gene therapy
Same as the full description in the CMS dataset.
Parent Code
Z92.8
Personal history of other medical treatment

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ92Personal history of medical treatment
This CodeZ92.86Personal history of gene therapy

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z92.86.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z92.86 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • History of gene therapy

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • History
      • personal (of)
        • gene therapy

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC030
Personal history of other disease
Default principal diagnosis: inpatient No · outpatient Yes

Code History & ChangesHistory

Replacement Z92.86 replaces the following previously assigned code(s):

  • Z92.89 - Personal history of other medical treatment
FY 2022AddedAdded to the ICD-10-CM code setEffective October 1, 2021.
FY 2023–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z92.86Overview

Is Z92.86 (Personal history of other medical treatment) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report personal history of gene therapy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z92.86 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because personal history of gene therapy describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z92.86 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for personal history of gene therapy on inpatient claims.