2026 ICD-10-CM Diagnosis Code T84.53XSInfection and inflammatory reaction due to internal right knee prosthesis, sequela
T84.53XS is a billable ICD-10-CM diagnosis code for infection and inflammatory reaction due to internal right knee prosthesis, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. Coders also document this condition as infection associated with prosthesis of right knee joint. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complication, sequela.
Code Identity
Code Classification
Present on Admission (POA)Billing
T84.53XS is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Infection associated with prosthesis of right knee joint
Coding GuidelinesGuidance
The appropriate 7th character is to be added to each code from block Complications of internal orthopedic prosthetic devices, implants and grafts (T84). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Knee Replacement
Knee replacement surgery is a surgery to replace parts of your knee joint with new, artificial parts. You may need a knee replacement if you have knee damage that causes severe pain and difficulty doing daily activities, such as walking and climbing stairs. It is usually done when other treatments for knee pain haven't helped enough.
The full article covers:
- What is knee replacement surgery?
- What conditions does knee replacement surgery treat?
- What happens during knee replacement surgery?
- What happens after knee replacement surgery?
- What is life like after a knee replacement?
- What are the risks of knee replacement surgery?
- How long does a knee replacement last?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T84.53XS to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T84.53XSOverview
Is T84.53XS a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report infection and inflammatory reaction due to internal right knee prosthesis, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character S in T84.53XS mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the infection and inflammatory reaction due to internal right knee prosthesis itself has resolved, not the original event.
What MS-DRG does T84.53XS group to?
When infection and inflammatory reaction due to internal right knee prosthesis, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.
Is T84.53XS exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for infection and inflammatory reaction due to internal right knee prosthesis, sequela on inpatient claims.
What is the ICD-9 equivalent of T84.53XS?
Under the General Equivalence Mappings, infection and inflammatory reaction due to internal right knee prosthesis, sequela converts to ICD-9-CM 909.3 (late eff surg/med compl). The mapping is approximate, so confirm the match fits the documentation.
