2027 ICD-10-CM Diagnosis Code R25.2Cramp and spasm

ICD-10-CM Codes›R00–R99›R25-R29›R25

ICD-10-CM R25.2
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R25.2 is a billable ICD-10-CM diagnosis code for cramp and spasm. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other general signs and symptoms.

Code Identity

ICD-10-CM Code
R25.2
Billable Status
Yes — Valid for Submission
Code Describes
Cramp and spasm
Short Description
Cramp and spasm
Same as the full description in the CMS dataset.
Parent Code
Abnormal involuntary movements

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR25-R29Symptoms and signs involving the nervous and musculoskeletal systems
CategoryR25Abnormal involuntary movements
This CodeR25.2Cramp and spasm

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acanthosis nigricans
  • Acanthosis nigricans and insulin resistance with muscle cramp and acral enlargement syndrome
  • Benign fasciculation-cramp syndrome
  • Bilateral cramp of muscle of lower limbs
  • Bilateral muscle cramp of upper limbs
  • Bowel spasm
  • Carney complex, trismus, pseudocamptodactyly syndrome
  • Central nervous system dysfunction in newborn
  • Clasp knife like increase in tone
  • Congenital hypoplasia of cerebral hemisphere
  • Congenital hypoplasia of cerebral white matter
  • Cortical visual impairment
  • Cramp
  • Cramp in foot
  • Cramp in limb
  • Cramp in lower leg
  • Cramp in lower limb
  • Cramp in muscle of thigh
  • Cramp in quadriceps muscle
  • Cramp of muscle of left lower limb
  • Cramp of muscle of left upper limb
  • Cramp of muscle of right lower limb
  • Cramp of muscle of right upper limb
  • Diffuse spasm
  • Disorders of spinal neurones manifest by hyperactivity
  • Early-onset progressive neurodegeneration, blindness, ataxia, spasticity syndrome
  • Hand cramps
  • Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps syndrome
  • Hypernatremia
  • Hypertonia of muscle of limb
  • Hypertonia of muscle of lower limb
  • Hypertonia of muscle of neck
  • Hypertonia of muscle of trunk
  • Hypomyelination with brain stem and spinal cord involvement and leg spasticity
  • Hypoplasia of corpus callosum
  • Infantile neurodegeneration, progressive spasticity, intellectual disability, white matter lesions syndrome
  • Insulin receptor defect
  • Intermittent painful muscle spasm
  • L1 syndrome
  • Lethal neonatal spasticity, epileptic encephalopathy syndrome
  • Local spasm
  • Masseter spasm
  • Microcephalus, brain defect, spasticity, hypernatremia syndrome
  • Muscular hypertonicity
  • Myxoma of heart
  • NESCAV syndrome
  • Nocturnal muscle cramp
  • Nocturnal muscle spasm
  • Peripheral axonal neuropathy
  • Spasm
  • Spasmodic movement
  • Spastic ataxia
  • Spastic foot
  • Spasticity
  • Spasticity as sequela of stroke
  • Tetanus with trismus
  • Trismus
  • Trismus following procedure on tooth
  • Trismus present
  • X-linked parkinsonism with spasticity syndrome
  • X-linked spasticity, intellectual disability, epilepsy syndrome

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R25.2: its own notes plus those printed at R25 and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From R25 Abnormal involuntary movements applies to 6 codes
  • specific movement disorders (G20-G26)
  • stereotyped movement disorders (F98.4)
  • tic disorders (F95.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

On R25.2 itself
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R25.2, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming R25.2: they are not reported together with it, unless the two conditions are unrelated.

  • M62 Other disorders of muscle
    cramp and spasm (R25.2)
  • F98.4 Stereotyped movement disorders
    abnormal involuntary movements (R25.-) names R25.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM016
Other general signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Muscle Cramp

    a sustained and usually painful contraction of muscle fibers. this may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., uremia; hypothyroidism; motor neuron disease; etc.). (from adams et al., principles of neurology, 6th ed, p1398)
  • Spasm

    an involuntary contraction of a muscle or group of muscles. spasms may involve skeletal muscle or smooth muscle.
  • Trismus

    spasmodic contraction of the masseter muscle resulting in forceful jaw closure. this may be seen with a variety of diseases, including tetanus, as a complication of radiation therapy, trauma, or in association with neoplastic conditions.

Patient EducationClinical

Muscle Cramps

Muscle cramps are sudden, involuntary contractions or spasms in one or more of your muscles. They are very common and often occur after exercise. Some people get muscle cramps, especially leg cramps, at night. They can be painful, and they may last a few seconds to several minutes.

The full article covers:

  • What are muscle cramps?
  • What causes muscle cramps?
  • Who is at risk for muscle cramps?
  • When do I need to see a health care provider for muscle cramps?
  • What are the treatments for muscle cramps?
  • Can muscle cramps be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R25.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
729.82 Cramp in limb
Approximate The match is approximate rather than exact.
ICD-9-CM
781.0 Abn involun movement NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R25.2Overview

What is the ICD-10 code for cramp and spasm?

The ICD-10-CM code for cramp and spasm is R25.2 (sometimes written as R252). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R25.2 (Abnormal involuntary movements) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cramp and spasm on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R25.2 group to?

When cramp and spasm is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R25.2 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the cramp and spasm is established, that condition takes the principal position instead.

Can R25.2 be reported with F98.4?

Not as a rule. The Excludes1 note at R25, which applies to R25.2, lists "stereotyped movement disorders (F98.4)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).