2027 ICD-10-CM Diagnosis Code P93.8Other reactions and intoxications due to drugs administered to newborn

ICD-10-CM Codes›P00–P96›P90-P96›P93

ICD-10-CM P93.8
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P93.8 is a billable ICD-10-CM diagnosis code for other reactions and intoxications due to drugs administered to newborn. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 4 closely related codes. Coders also document this condition as drug reaction AND/OR intoxication specific to newborn. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Other specified and unspecified perinatal conditions.

For Medicare Advantage risk adjustment, P93.8 maps to CMS-HCC Category 137 (Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications) under the V28 model, adding a risk factor of about 0.424 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
P93.8
Billable Status
Yes — Valid for Submission
Code Describes
Other reactions and intoxications due to drugs administered to newborn
Short Description
Oth reactions and intoxications d/t drugs administered to NB
Parent Code
Reactions and intoxications due to drugs administered to newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP90-P96Other disorders originating in the perinatal period
CategoryP93Reactions and intoxications due to drugs administered to newborn
This CodeP93.8Other reactions and intoxications due to drugs administered to newborn

Medicare Risk Adjustment (HCC)Billing

P93.8 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 137— Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
Payment HCC · PY 2027 one of 308 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.424
community, non-dual, aged · ranges 0.297–0.502 across segments
Hierarchy
Superseded by HCC 135 and HCC 136
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Part D (RxHCC)
Not mapped
P93.8 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Drug reaction AND/OR intoxication specific to newborn
  • Neonatal drug reaction and intoxication
  • Newborn drug intoxication
  • Newborn drug reaction

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P93.8: its own notes plus those printed at P93 and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From P93 Reactions and intoxications due to drugs administered to newborn applies to 2 codes
  • reactions and intoxications due to drugs administered to fetus affecting newborn
From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From P93 Reactions and intoxications due to drugs administered to newborn applies to 2 codes
  • jaundice due to drugs or toxins transmitted from mother or given to newborn (P58.4-)
  • reactions and intoxications from maternal opiates, tranquilizers and other medication (P04.0-P04.1, P04.4-)
  • withdrawal symptoms from maternal use of drugs of addiction (P96.1)
  • withdrawal symptoms from therapeutic use of drugs in newborn (P96.2)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR PNL013
Other specified and unspecified perinatal conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

The full article covers:

  • What is a drug interaction?
  • What are side effects?
  • What are drug allergies?
  • How can I stay safe when taking medicines?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P93.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
779.4 NB drug reaction/intoxic
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P93.8Overview

What is the ICD-10 code for other reactions and intoxications due to drugs administered to newborn?

The ICD-10-CM code for other reactions and intoxications due to drugs administered to newborn is P93.8 (sometimes written as P938). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P93.8 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other reactions and intoxications due to drugs administered to newborn on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P93.8 group to?

When other reactions and intoxications due to drugs administered to newborn is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P93.8 a CC or MCC?

CMS lists P93.8 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 4 closely related codes in its exclusion list.

Can P93.8 be reported with a code from P58.4?

Not as a rule. The Excludes1 note at P93, which applies to P93.8, lists "jaundice due to drugs or toxins transmitted from mother or given to newborn (P58.4-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is P93.8?

P93.8 (other reactions and intoxications due to drugs administered to newborn) maps to CMS-HCC Category 137 (Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications), commonly written as HCC 137, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It does not map to any RxHCC in the Part D prescription drug model.

Does P93.8 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, P93.8 adds a risk adjustment factor of about 0.424 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.297 to 0.502 depending on the payment segment). A more severe related category (HCC 135 and HCC 136) supersedes it when both are reported. See the full factor table on the HCC 137 category page.