Disorders of muscle tone of newborn (P94)

• ICD-10 Index

  • Certain conditions originating in the perinatal period (P00–P96)

    • Other disorders originating in the perinatal period (P90-P96)

      • Disorders of muscle tone of newborn (P94)

        • P94 - Disorders of muscle tone of newborn NON-BILLABLE CODE
        • P94.0 - Transient neonatal myasthenia gravis BILLABLE CODE
        • P94.1 - Congenital hypertonia BILLABLE CODE
        • P94.2 - Congenital hypotonia BILLABLE CODE
        • P94.8 - Other disorders of muscle tone of newborn BILLABLE CODE
        • P94.9 - Disorder of muscle tone of newborn, unspecified BILLABLE CODE

Clinical Information for Disorders of muscle tone of newborn (P94)

Myasthenia Gravis - A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Cystinuria - An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.

Myasthenia Gravis, Autoimmune, Experimental - Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)

Myasthenic Syndromes, Congenital - A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes presynaptic, synaptic, and postsynaptic disorders (that are not of autoimmune origin). The majority of these diseases are caused by mutations of various subunits of the nicotinic acetylcholine receptor (RECEPTORS, NICOTINIC) on the postsynaptic surface of the junction. (From Arch Neurol 1999 Feb;56(2):163-7)