2026 ICD-10-CM Diagnosis Code K86.81Exocrine pancreatic insufficiency

ICD-10-CM CodesK00–K95K80-K87K86

ICD-10-CM K86.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K86.81 is a billable ICD-10-CM diagnosis code for exocrine pancreatic insufficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 438 through 440. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Pancreatic disorders (excluding diabetes).

Code Identity

ICD-10-CM Code
K86.81
Billable Status
Yes — Valid for Submission
Code Describes
Exocrine pancreatic insufficiency
Short Description
Exocrine pancreatic insufficiency
Same as the full description in the CMS dataset.
Parent Code
Other specified diseases of pancreas

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK80-K87Disorders of gallbladder, biliary tract and pancreas
CategoryK86Other diseases of pancreas
This CodeK86.81Exocrine pancreatic insufficiency

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Exocrine pancreatic insufficiency
  • Pancreatic insufficiency

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Insufficiency, insufficient
      • pancreatic
        • exocrine

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG020
Pancreatic disorders (excluding diabetes)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Exocrine Pancreatic Insufficiency

    a malabsorption condition resulting from greater than 10% reduction in the secretion of pancreatic digestive enzymes (lipase; proteases; and amylase) by the exocrine pancreas into the duodenum. this condition is often associated with cystic fibrosis and with chronic pancreatitis.

Patient EducationClinical

Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K86.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
577.8 Pancreatic disease NEC
Approximate The match is approximate rather than exact.

Code History & ChangesHistory

Replacement K86.81 replaces the following previously assigned code(s):

  • K86.8 - Other specified diseases of pancreas
FY 2018AddedAdded to the ICD-10-CM code setEffective October 1, 2017.
FY 2019–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K86.81Overview

Is K86.81 (Other specified diseases of pancreas) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report exocrine pancreatic insufficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K86.81 group to?

When exocrine pancreatic insufficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 438, 439, 440, with relative weights from 0.6214 to 1.6302 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K86.81?

Under the General Equivalence Mappings, exocrine pancreatic insufficiency converts to ICD-9-CM 577.8 (pancreatic disease NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.