2022 ICD-10-CM Code C25

Malignant neoplasm of pancreas

Version 2021

Not Valid for Submission

ICD-10:C25
Short Description:Malignant neoplasm of pancreas
Long Description:Malignant neoplasm of pancreas

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of digestive organs (C15-C26)
      • Malignant neoplasm of pancreas (C25)

C25 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of malignant neoplasm of pancreas. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Malignant neoplasm of pancreas

Non-specific codes like C25 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for malignant neoplasm of pancreas:

  • BILLABLE CODE - Use C25.0 for Malignant neoplasm of head of pancreas
  • BILLABLE CODE - Use C25.1 for Malignant neoplasm of body of pancreas
  • BILLABLE CODE - Use C25.2 for Malignant neoplasm of tail of pancreas
  • BILLABLE CODE - Use C25.3 for Malignant neoplasm of pancreatic duct
  • BILLABLE CODE - Use C25.4 for Malignant neoplasm of endocrine pancreas
  • BILLABLE CODE - Use C25.7 for Malignant neoplasm of other parts of pancreas
  • BILLABLE CODE - Use C25.8 for Malignant neoplasm of overlapping sites of pancreas
  • BILLABLE CODE - Use C25.9 for Malignant neoplasm of pancreas, unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code C25:


Code Also

Code Also
A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.

Use Additional Code

Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

Information for Patients


Pancreatic Cancer

The pancreas is a gland behind your stomach and in front of your spine. It produces the juices that help break down food and the hormones that help control blood sugar levels. Pancreatic cancer usually begins in the cells that produce the juices. Some risk factors for developing pancreatic cancer include

Pancreatic cancer is hard to catch early. It doesn't cause symptoms right away. When you do get symptoms, they are often vague or you may not notice them. They include yellowing of the skin and eyes, pain in the abdomen and back, weight loss and fatigue. Also, because the pancreas is hidden behind other organs, health care providers cannot see or feel the tumors during routine exams. Doctors use a physical exam, blood tests, imaging tests, and a biopsy to diagnose it.

Because it is often found late and it spreads quickly, pancreatic cancer can be hard to treat. Possible treatments include surgery, radiation, chemotherapy, and targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Pancreatic Cancer Summary Learn about pancreatic cancer risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)