2026 ICD-10-CM Diagnosis Code K52.1Toxic gastroenteritis and colitis
ICD-10-CM Codes›K00–K95›K50-K52›K52
- Billable — Valid for Submission
- Not Chronic
K52.1 is a billable ICD-10-CM diagnosis code for toxic gastroenteritis and colitis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 393 through 395. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Noninfectious gastroenteritis.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Antibiotic enterocolitis
- Antibiotic-associated diarrhea
- Chemical colitis
- Diarrhea caused by alcohol intake
- Diarrhea caused by drug
- Diarrhea caused by ingestion of unabsorbable substances
- Diarrhea due to harmful pattern of laxative use
- Diarrheic shellfish poisoning
- Drug-induced colitis
- Drug-induced enteritis of intestine
- Gastritis medicamentosa
- Gastroenteritis caused by drug
- Immune checkpoint inhibitor therapy induced enterocolitis
- Malabsorption caused by drug
- Non-infective diarrhea
- Noninfective enteritis and colitis
- Non-steroidal anti-inflammatory drug-induced colitis
- Non-steroidal anti-inflammatory drug-induced enteropathy
- Osmotic diarrhea
- Soap colitis
- Toxic effect from eating shellfish
- Toxic enteritis of small intestine
- Toxic enteritis of small intestine caused by drug
- Toxic gastroenteritis
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Drug-induced gastroenteritis and colitis
Code First
Use Additional Code
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Colitis (acute) (catarrhal) (chronic) (noninfective) (hemorrhagic) - See Also: Enteritis; - K52.9
- drug-induced - K52.1
- toxic NEC - K52.1
- Diarrhea, diarrheal (disease) (infantile) (inflammatory) - R19.7
- drug-induced - K52.1
- due to
- drugs - K52.1
- toxic - K52.1
- Enteritis (acute) (diarrheal) (hemorrhagic) (noninfective) - K52.9
- drug-induced - K52.1
- due to
- drugs - K52.1
- toxic NEC - K52.1
- Gastroenteritis (acute) (chronic) (noninfectious) - See Also: Enteritis; - K52.9
- drug-induced - K52.1
- due to
- drugs - K52.1
- toxic - K52.1
- alimentary canal - K52.1
- enteric - K52.1
- gastrointestinal - K52.1
- gastrointestinal - K52.1
- intestinal - K52.1
- small intestine - K52.1
- Toxinfection, gastrointestinal - K52.1
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Colitis(acute) (catarrhal) (chronic) (noninfective) (hemorrhagic)
- drug-induced
- Colitis(acute) (catarrhal) (chronic) (noninfective) (hemorrhagic)
- toxic NEC
- Diarrhea, diarrheal(disease) (infantile) (inflammatory)
- drug-induced
- Diarrhea, diarrheal(disease) (infantile) (inflammatory)
- due to
- drugs
- Diarrhea, diarrheal(disease) (infantile) (inflammatory)
- toxic
- Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
- drug-induced
- Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
- due to
- drugs
- Enteritis(acute) (diarrheal) (hemorrhagic) (noninfective)
- toxic NEC
- Gastroenteritis(acute) (chronic) (noninfectious)
- drug-induced
- Gastroenteritis(acute) (chronic) (noninfectious)
- due to
- drugs
- Gastroenteritis(acute) (chronic) (noninfectious)
- toxic
- Intoxication
- alimentary canal
- Intoxication
- enteric
- Intoxication
- gastrointestinal
- Toxemia
- gastrointestinal
- Toxemia
- intestinal
- Toxemia
- small intestine
- Toxinfection, gastrointestinal
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Gastroenteritis
Gastroenteritis is an inflammation of the lining of the stomach and intestines. The main symptoms include vomiting and diarrhea. It is usually not serious in healthy people, but it can sometimes lead to dehydration or cause severe symptoms.
The full article covers:
- What is gastroenteritis?
- What causes gastroenteritis?
- What are the symptoms of gastroenteritis?
- How is gastroenteritis diagnosed?
- What are the treatments for gastroenteritis?
- Can gastroenteritis be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert K52.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About K52.1Overview
Is K52.1 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report toxic gastroenteritis and colitis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does K52.1 group to?
When toxic gastroenteritis and colitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 393, 394, 395, with relative weights from 0.6490 to 1.5993 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of K52.1?
Under the General Equivalence Mappings, toxic gastroenteritis and colitis converts to ICD-9-CM 558.2 (toxic gastroenteritis). The mapping is a direct match.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
