2026 ICD-10-CM Diagnosis Code I95.3Hypotension of hemodialysis

ICD-10-CM Codes›I00–I99›I95-I99›I95

ICD-10-CM I95.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I95.3 is a billable ICD-10-CM diagnosis code for hypotension of hemodialysis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as dialysis fluid adverse reaction. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hypotension.

Code Identity

ICD-10-CM Code
I95.3
Billable Status
Yes — Valid for Submission
Code Describes
Hypotension of hemodialysis
Short Description
Hypotension of hemodialysis
Same as the full description in the CMS dataset.
Parent Code
I95
Hypotension

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI95-I99Other and unspecified disorders of the circulatory system
CategoryI95Hypotension
This CodeI95.3Hypotension of hemodialysis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Dialysis fluid adverse reaction
  • Hemodialysis fluid adverse reaction
  • Hemodialysis-associated hypotension

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Intra-dialytic hypotension

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Hypotension(arterial) (constitutional)
      • due to (of) hemodialysis
    • Hypotension(arterial) (constitutional)
      • intra-dialytic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR031
Hypotension
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypotension

    abnormally low blood pressure that can result in inadequate blood flow to the brain and other vital organs. common symptom is dizziness but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

  • Hypotension, Controlled

    procedure in which arterial blood pressure is intentionally reduced in order to control blood loss during surgery. this procedure is performed either pharmacologically or by pre-surgical removal of blood.

  • Hypotension, Orthostatic

    a significant drop in blood pressure after assuming a standing position. orthostatic hypotension is a finding, and defined as a 20-mm hg decrease in systolic pressure or a 10-mm hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. symptoms generally include dizziness, blurred vision, and syncope.

  • Intracranial Hypotension

    reduction of cerebrospinal fluid pressure characterized clinically by orthostatic headache and occasionally by an abducens nerve palsy; hearing loss; nausea; neck stiffness, and other symptoms. this condition may be spontaneous or secondary to cerebrospinal fluid leak; spinal puncture; neurosurgical procedures; dehydration; uremia; trauma (see also craniocerebral trauma); and other processes. chronic hypotension may be associated with subdural hematomas (see hematoma, subdural) or hygromas. (from semin neurol 1996 mar;16(1):5-10; adams et al., principles of neurology, 6th ed, pp637-8)

  • Ocular Hypotension

    abnormally low intraocular pressure often related to chronic inflammation (uveitis).

  • Post-Exercise Hypotension

    transient reduction in blood pressure levels immediately after exercises that lasts 2-12 hours. the reduction varies but is typically 5-20 mm hg when compared to pre-exercise levels. it exists both in normotensive and hypertensive individuals and may play a role in excercise related physiologic adaptation.

  • Shy-Drager Syndrome

    a progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. this disease is generally considered a clinical variant of multiple system atrophy. affected individuals present in the fifth or sixth decade with orthostasis and bladder dysfunction; and later develop fecal incontinence; anhidrosis; ataxia; impotence; and alterations of tone suggestive of basal ganglia dysfunction. (from adams et al., principles of neurology, 6th ed, p536)

  • Adaptation, Physiological

    the non-genetic biological changes of an organism in response to challenges in its environment.

Patient EducationClinical

Dialysis

When your kidneys are healthy, they clean your blood. They also make hormones that keep your bones strong and your blood healthy. When your kidneys fail, you need treatment to replace the work your kidneys used to do. Unless you have a kidney transplant, you will need a treatment called dialysis.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I95.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
458.21 Hemododialysis hypotensn
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I95.3Overview

Is I95.3 (Hypotension) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hypotension of hemodialysis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of I95.3?

Under the General Equivalence Mappings, hypotension of hemodialysis converts to ICD-9-CM 458.21 (hemododialysis hypotensn). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.