2026 ICD-10-CM Diagnosis Code G37.89Other specified demyelinating diseases of central nervous system

ICD-10-CM CodesG00–G99G35-G37G37

ICD-10-CM G37.89
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

G37.89 is a billable ICD-10-CM diagnosis code for other specified demyelinating diseases of central nervous system. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative).

Code Identity

ICD-10-CM Code
G37.89
Billable Status
Yes — Valid for Submission
Code Describes
Other specified demyelinating diseases of central nervous system
Short Description
Other specified demyelinating diseases of cnsl
Parent Code
Other specified demyelinating diseases of central nervous system

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG35-G37Demyelinating diseases of the central nervous system
CategoryG37Other demyelinating diseases of central nervous system
This CodeG37.89Other specified demyelinating diseases of central nervous system

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • 4H leukodystrophy
  • Central nervous system demyelination due to Lyme borreliosis
  • Central pontine myelinolysis
  • Clinically isolated syndrome
  • Clinically isolated syndrome of brainstem
  • Clinically isolated syndrome of cerebellum
  • Demyelination due to systemic vasculitis
  • Demyelination of central nervous system due to Behcet disease
  • Extrapontine myelinolysis
  • Hypomyelination of early myelinating structures
  • Inherited disorder of folate metabolism
  • Late tooth eruption
  • Leukoencephalopathy, ataxia, hypodontia, hypomyelination syndrome
  • Mitchell syndrome
  • Mixed sensory-motor polyneuropathy
  • Monofocal clinically isolated syndrome
  • Motor polyneuropathy
  • MTHFS-related developmental delay, microcephaly, short stature, epilepsy syndrome
  • Mucocutaneous Behçet disease
  • Multifocal clinically isolated syndrome
  • Osmotic demyelination syndrome
  • Radiologically isolated syndrome
  • Sensory polyneuropathy
  • Vasculitis due to systemic disease

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Demyelination, demyelinization
      • central nervous system
        • specified NEC
    • Disease, diseased
      • demyelinating, demyelinizating (nervous system)
        • specified NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Code History & ChangesHistory

Replacement G37.89 replaces the following previously assigned code(s):

  • G37.8 - Oth demyelinating diseases of central nervous system
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About G37.89Overview

Is G37.89 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified demyelinating diseases of central nervous system on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.