2026 ICD-10-CM Diagnosis Code G37.81Myelin oligodendrocyte glycoprotein antibody disease

ICD-10-CM Codes›G00–G99›G35-G37›G37

ICD-10-CM G37.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

G37.81 is a billable ICD-10-CM diagnosis code for myelin oligodendrocyte glycoprotein antibody disease. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as myelin oligodendrocyte glycoprotein antibody-associated disease. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative).

Code Identity

ICD-10-CM Code
G37.81
Billable Status
Yes — Valid for Submission
Code Describes
Myelin oligodendrocyte glycoprotein antibody disease
Short Description
Myelin oligodendrocyte glycoprotein antibody disease
Same as the full description in the CMS dataset.
Parent Code
G37.8
Other specified demyelinating diseases of central nervous system

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG35-G37Demyelinating diseases of the central nervous system
CategoryG37Other demyelinating diseases of central nervous system
This CodeG37.81Myelin oligodendrocyte glycoprotein antibody disease

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Myelin oligodendrocyte glycoprotein antibody-associated disease

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • MOG antibody disease

Code Also

  • associated manifestations, if known, such as:
  • noninfectious acute disseminated encephalomyelitis G04.81
  • neuromyelitis optica G36.0

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • MOG antibody
    • Disease, diseased
      • myelin oligodendrocyte glycoprotein antibody
    • MOGAD(myelin oligodendrocyte glycoprotein antibody disease)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Code History & ChangesHistory

Replacement G37.81 replaces the following previously assigned code(s):

  • G37.8 - Oth demyelinating diseases of central nervous system
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About G37.81Overview

Is G37.81 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report myelin oligodendrocyte glycoprotein antibody disease on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.