2026 ICD-10-CM Diagnosis Code D83.8Other common variable immunodeficiencies

ICD-10-CM Codes›D50–D89›D80-D89›D83

ICD-10-CM D83.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D83.8 is a billable ICD-10-CM diagnosis code for other common variable immunodeficiencies. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Immunity disorders.

Code Identity

ICD-10-CM Code
D83.8
Billable Status
Yes — Valid for Submission
Code Describes
Other common variable immunodeficiencies
Short Description
Other common variable immunodeficiencies
Same as the full description in the CMS dataset.
Parent Code
D83
Common variable immunodeficiency

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD80-D89Certain disorders involving the immune mechanism
CategoryD83Common variable immunodeficiency
This CodeD83.8Other common variable immunodeficiencies

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Autosomal dominant combined variable immunodeficiency due to IRF2BP2 mutation
  • Autosomal dominant combined variable immunodeficiency due to NFKB1 mutation
  • Autosomal dominant combined variable immunodeficiency due to SEC61A1 mutation
  • Autosomal dominant combined variable immunodeficiency due to TWEAK mutation
  • Autosomal recessive combined variable immunodeficiency due to ARHGEF1 mutation
  • Autosomal recessive combined variable immunodeficiency due to BAFF receptor deficiency
  • Autosomal recessive combined variable immunodeficiency due to PIK3CG mutation
  • Autosomal recessive common variable immunodeficiency due to CD20 mutation
  • Autosomal recessive common variable immunodeficiency due to CD21 mutation
  • Autosomal recessive common variable immunodeficiency due to CD81 deficiency
  • Autosomal recessive common variable immunodeficiency due to POU2AF1 mutation
  • Autosomal recessive common variable immunodeficiency due to RAC2 deficiency
  • Common variable immunodeficiency due to TACI deficiency
  • X-linked common variable immunodeficiency due to SH3KBP1 deficiency

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Immunodeficiency
      • common variable
        • specified type NEC
    • Syndrome
      • Good's

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD008
Immunity disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Common Variable Immunodeficiency

    heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable b-cell defects, and the presence of recurrent bacterial infections.

Patient EducationClinical

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.

The full article covers:

  • What is the immune system?
  • What are the parts of the immune system?
  • How does the immune system work?
  • What are the types of immunity?
  • What can go wrong with the immune system?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D83.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
279.06 Common variabl immunodef
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D83.8Overview

Is D83.8 (Common variable immunodeficiency) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other common variable immunodeficiencies on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D83.8 group to?

When other common variable immunodeficiencies is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D83.8?

Under the General Equivalence Mappings, other common variable immunodeficiencies converts to ICD-9-CM 279.06 (common variabl immunodef). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.