2026 ICD-10-CM Diagnosis Code D68.62Lupus anticoagulant syndrome

ICD-10-CM Codes›D50–D89›D65-D69›D68

ICD-10-CM D68.62
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D68.62 is a billable ICD-10-CM diagnosis code for lupus anticoagulant syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 40 closely related codes. Coders also document this condition as antiphospholipid syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

D68.62 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 48 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 48, ESRD (V21) category 48, and ESRD (V24) category 48 for payment year 2026.

Code Identity

ICD-10-CM Code
D68.62
Billable Status
Yes — Valid for Submission
Code Describes
Lupus anticoagulant syndrome
Short Description
Lupus anticoagulant syndrome
Same as the full description in the CMS dataset.
Parent Code
Other thrombophilia

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD65-D69Coagulation defects, purpura and other hemorrhagic conditions
CategoryD68Other coagulation defects
This CodeD68.62Lupus anticoagulant syndrome

Medicare Risk Adjustment (HCC)Billing

D68.62 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
Dropped in V28 see all codes that no longer risk-adjust
Prior Model (CMS-HCC V24)
HCC 48
V24 retired last contributed to a Medicare Advantage risk score in payment year 2025
Other CMS Models
PACE (CMS-HCC V22): HCC 48 · ESRD (V21): HCC 48 · ESRD (V24): HCC 48
ESRD V21 weights: 0.059 dialysis, 0.173–0.234 functioning graft · ESRD V24 weights: 0.063 dialysis, 0.192–0.358 functioning graft
Part D (RxHCC)
Not mapped
D68.62 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Antiphospholipid syndrome
  • Lupus anticoagulant disorder
  • Secondary antiphospholipid syndrome
  • Systemic lupus erythematosus-associated antiphospholipid syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Lupus anticoagulant
  • Presence of systemic lupus erythematosus [SLE] inhibitor

Type 1 Excludes

  • lupus anticoagulant LAC finding without diagnosis R76.0

Type 2 Excludes

  • anticardiolipin syndrome D68.61
  • antiphospholipid syndrome D68.61
  • lupus anticoagulant LAC with hemorrhagic disorder D68.312

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Antiphospholipid Syndrome

    the presence of antibodies directed against phospholipids (antibodies, antiphospholipid). the condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. in pregnancy it can cause abortion. of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (antibodies, anticardiolipin). present also are high levels of lupus anticoagulant (lupus coagulation inhibitor).
  • Lupus Anticoagulant Disorder

    a hypercoaguable state that results from the presence of the immunoglobulin known as lupus anticoagulant. the antibody interacts with cell membrane phospholipids, causing increased aggregation and adhesion of platelets, which causes increased clot formation. though the majority of patients who test positive for lupus anticoagulant do not have lupus, those individuals afflicted with lupus have a higher probability of developing the antibody.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D68.62 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.81 Prim hypercoagulable st
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D68.62Overview

What is the ICD-10 code for lupus anticoagulant syndrome?

The ICD-10-CM code for lupus anticoagulant syndrome is D68.62 (sometimes written as D6862). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is D68.62 (Other thrombophilia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report lupus anticoagulant syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D68.62 group to?

When lupus anticoagulant syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

Is D68.62 a CC or MCC?

CMS lists D68.62 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 40 closely related codes in its exclusion list.

What is the ICD-9 equivalent of D68.62?

Under the General Equivalence Mappings, lupus anticoagulant syndrome converts to ICD-9-CM 289.81 (prim hypercoagulable st). The mapping is approximate, so confirm the match fits the documentation.

Does D68.62 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage. D68.62 mapped to HCC 48 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V21) category 48 (Coagulation Defects and Other Specified Hematological Disorders), and ESRD (V24) category 48 (Coagulation Defects and Other Specified Hematological Disorders).