2027 ICD-10-CM Diagnosis Code D41.22Neoplasm of uncertain behavior of left ureter

ICD-10-CM Codes›C00–D49›D37-D48›D41

ICD-10-CM D41.22
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D41.22 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of left ureter. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 656 through 658, 686 through 688. Coders also document this condition as bilateral neoplasm of uncertain behavior of ureters. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D41.22
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of uncertain behavior of left ureter
Short Description
Neoplasm of uncertain behavior of left ureter
Same as the full description in the CMS dataset.
Parent Code
D41.2
Neoplasm of uncertain behavior of ureter

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD41Neoplasm of uncertain behavior of urinary organs
This CodeD41.22Neoplasm of uncertain behavior of left ureter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral neoplasm of uncertain behavior of ureters
  • Neoplasm of uncertain behavior of left ureter
  • Neoplasm of uncertain behavior of right ureter
  • Neoplasm of uncertain behavior of ureter

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D41.22: its own notes plus those printed at block D37-D48 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes applies to 137 codes
  • neoplasms of unspecified behavior (D49.-)

Notes

General instructions on how these codes are used.

From Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes applies to 137 codes
  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D41.22, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming D41.22: its condition is not part of those codes, and both may be reported when the patient has both.

  • D49 Neoplasms of unspecified behavior
    neoplasms of uncertain behavior (D37-D44, D48) names D37-D44, which includes this code

Notes 1

These notes mention D41.22.

  • Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
    Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made. names D37-D44, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
ureter, ureteralC66.C79.19D09.19D30.2D41.2D49.59

Patient EducationClinical

Ureteral Disorders

Your kidneys make urine by filtering wastes and extra water from your blood. The urine travels from the kidneys to the bladder in two thin tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D41.22 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
236.91 Unc behav neo kidney
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D41.22Overview

What is the ICD-10 code for neoplasm of uncertain behavior of left ureter?

The ICD-10-CM code for neoplasm of uncertain behavior of left ureter is D41.22 (sometimes written as D4122). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D41.22 (Neoplasm of uncertain behavior of ureter) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of left ureter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D41.22 group to?

When neoplasm of uncertain behavior of left ureter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 656, 687, 658, 657, 686, 688, with relative weights from 0.7332 to 3.2782 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D41.22 be reported with a code from D49?

Not as a rule. The Excludes1 note at block D37-D48, which applies to D41.22, lists "neoplasms of unspecified behavior (D49.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D41.22?

Under the General Equivalence Mappings, neoplasm of uncertain behavior of left ureter converts to ICD-9-CM 236.91 (unc behav neo kidney). The mapping is approximate, so confirm the match fits the documentation.