2026 ICD-10-CM Diagnosis Code C85.80Other specified types of non-Hodgkin lymphoma, unspecified site

ICD-10-CM CodesC00–D49C81-C96C85

ICD-10-CM C85.80
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C85.80 is a billable ICD-10-CM diagnosis code for other specified types of non-Hodgkin lymphoma, unspecified site. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 820 through 825, 840 through 842, 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Non-Hodgkin lymphoma.

Code Identity

ICD-10-CM Code
C85.80
Billable Status
Yes — Valid for Submission
Code Describes
Other specified types of non-Hodgkin lymphoma, unspecified site
Short Description
Oth types of non-Hodgkin lymphoma, unspecified site
Parent Code
Other specified types of non-Hodgkin lymphoma

Code Classification

ChapterC00–D49Neoplasms
SectionC81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
CategoryC85Other specified and unspecified types of non-Hodgkin lymphoma
This CodeC85.80Other specified types of non-Hodgkin lymphoma, unspecified site

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cerebral degeneration due to neoplastic disease
  • Diffuse high grade B-cell lymphoma
  • Diffuse large B-cell lymphoma
  • Diffuse low grade B-cell lymphoma
  • Diffuse malignant lymphoma - small non-cleaved cell
  • Diffuse non-Hodgkin immunoblastic lymphoma co-occurrent with human immunodeficiency virus infection
  • Diffuse non-Hodgkin's lymphoma
  • Diffuse non-Hodgkin's lymphoma, immunoblastic
  • Diffuse non-Hodgkin's lymphoma, small cleaved cell
  • Diffuse non-Hodgkin's lymphoma, undifferentiated
  • Follicular low grade B-cell lymphoma
  • Follicular malignant lymphoma - mixed cell type
  • Follicular non-Hodgkin's mixed small cleaved and large cell lymphoma
  • Malignant lymphoma - lymphocytic, intermediate differentiation
  • Malignant lymphoma, centroblastic type, follicular
  • Malignant lymphoma, lymphocytic, poorly differentiated, nodular
  • Malignant neoplastic disease co-occurrent with human immunodeficiency virus infection
  • Nodular high grade B-cell lymphoma
  • Nodular lymphoma
  • Prethymic and thymic T-cell lymphoma/leukemia
  • Proliferating angioendotheliomatosis
  • Prolymphocytic lymphosarcoma
  • White matter disease due to microglioma

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO058
Non-Hodgkin lymphoma
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Lymphoma

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C85.80 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
202.80 Oth lymp unsp xtrndl org
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C85.80Overview

Is C85.80 (Other specified types of non-Hodgkin lymphoma) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified types of non-Hodgkin lymphoma, unspecified site on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C85.80 group to?

When other specified types of non-Hodgkin lymphoma, unspecified site is the principal diagnosis on an inpatient stay, it groups to MS-DRG 820, 821, 822, 823, 824, 825, 840, 841, 842, 974, 975, 976, with relative weights from 0.8945 to 5.8648 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C85.80?

Under the General Equivalence Mappings, other specified types of non-Hodgkin lymphoma, unspecified site converts to ICD-9-CM 202.80 (oth lymp unsp xtrndl org). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.