2026 ICD-10-CM Diagnosis Code C75.2Malignant neoplasm of craniopharyngeal duct

ICD-10-CM Codes›C00–D49›C73-C75›C75

ICD-10-CM C75.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C75.2 is a billable ICD-10-CM diagnosis code for malignant neoplasm of craniopharyngeal duct. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Endocrine system cancers - all other types.

Code Identity

ICD-10-CM Code
C75.2
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of craniopharyngeal duct
Short Description
Malignant neoplasm of craniopharyngeal duct
Same as the full description in the CMS dataset.
Parent Code
C75
Malignant neoplasm of other endocrine glands and related structures

Code Classification

ChapterC00–D49Neoplasms
SectionC73-C75Malignant neoplasms of thyroid and other endocrine glands
CategoryC75Malignant neoplasm of other endocrine glands and related structures
This CodeC75.2Malignant neoplasm of craniopharyngeal duct

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Malignant neoplasm of craniopharyngeal duct
  • Malignant neoplasm of pituitary gland and craniopharyngeal duct
  • Neoplasm of craniopharyngeal duct
  • Primary malignant neoplasm of craniopharyngeal duct
  • Primary malignant neoplasm of pituitary gland

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO056
Endocrine system cancers - all other types
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
craniobuccal pouchC75.2C79.89D09.3D35.2D44.3D49.7
craniopharyngeal (duct) (pouch)C75.2C79.89D09.3D35.3D44.4D49.7

Patient EducationClinical

Pituitary Tumors

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C75.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
194.3 Malig neo pituitary
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C75.2Overview

Is C75.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of craniopharyngeal duct on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C75.2 group to?

When malignant neoplasm of craniopharyngeal duct is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C75.2?

Under the General Equivalence Mappings, malignant neoplasm of craniopharyngeal duct converts to ICD-9-CM 194.3 (malig neo pituitary). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.