2027 ICD-10-CM Diagnosis Code R89.2Abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues
ICD-10-CM Codes›R00–R99›R83-R89›R89
- Billable — Valid for Submission
- Not Chronic
R89.2 is a billable ICD-10-CM diagnosis code for abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Biotin above reference range
- Biotin below reference range
- Bone marrow iron finding
- Carbamazepine level - finding
- Carbamazepine level above reference range
- Carbamazepine level below reference range
- Carotene above reference range
- Carotene below reference range
- Coproporphyrin above reference range
- Coproporphyrin below reference range
- Decreased bone marrow iron
- Digoxin level - finding
- Digoxin level above therapeutic range
- Digoxin level below therapeutic range
- Fecal chymotrypsin
- Finding of theophylline level
- Increased bone marrow iron
- Lithium level - finding
- Lithium level below therapeutic range
- Lithium level high - toxic
- Opiate detected by screening method
- Pantothenic acid above reference range
- Pantothenic acid below reference range
- Phenobarbitone level - finding
- Phenobarbitone level above therapeutic range
- Phenobarbitone level below therapeutic range
- Phenytoin level - finding
- Phenytoin level above therapeutic range
- Phenytoin level below reference range
- Porphyrin above reference range
- Porphyrin below reference range
- Protoporphyrin above reference range
- Protoporphyrin below reference range
- Theophylline level above therapeutic range
- Theophylline level below therapeutic range
- Uroporphyrin above reference range
- Valproate level - finding
- Valproate level above reference range
- Vitamin B above reference range
- Vitamin K above reference range
- Vitamin K2 above reference range
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to R89.2: its own notes plus those printed at R89, block R83-R89, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- abnormal findings in nipple discharge
- abnormal findings in synovial fluid
- abnormal findings in wound secretions
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- abnormal findings on antenatal screening of mother (O28.-)
- diagnostic abnormal findings classified elsewhere - see Alphabetical Index
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Notes
General instructions on how these codes are used.
- This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
- Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
- The conditions and signs or symptoms included in categories R00-R94 consist of:
- (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
- (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
- (c) provisional diagnosis in a patient who failed to return for further investigation or care;
- (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
- (e) cases in which a more precise diagnosis was not available for any other reason;
- (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name R89.2, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Abnormal, abnormality, abnormalities See Also: Anomaly;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Convert R89.2 to ICD-9-CMHistory
Code HistoryHistory
Questions About R89.2Overview
Is R89.2 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does R89.2 group to?
When abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues is the principal diagnosis on an inpatient stay, it groups to MS-DRG 948, 947, with relative weights from 0.7833 to 1.2608 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R89.2 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues is established, that condition takes the principal position instead.
Can R89.2 be reported with a code from O28?
Not as a rule. The Excludes1 note at block R83-R89, which applies to R89.2, lists "abnormal findings on antenatal screening of mother (O28.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of R89.2?
Under the General Equivalence Mappings, abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues converts to ICD-9-CM 792.9 (abn find-body subst NEC) and 796.0 (abn toxicologic finding). The mapping is approximate, so confirm the match fits the documentation.
