2026 ICD-10-CM Diagnosis Code R82.5Elevated urine levels of drugs, medicaments and biological substances
ICD-10-CM Codes›R00–R99›R80-R82›R82
- Billable — Valid for Submission
- Not Chronic
R82.5 is a billable ICD-10-CM diagnosis code for elevated urine levels of drugs, medicaments and biological substances. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 695 through 696. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Genitourinary signs and symptoms.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- 17-ketogenic steroids level above reference range
- 17-ketosteroids level above reference range
- Acetaminophen in urine
- Amphetamine in urine
- Epinephrine level above reference range
- High 17-ketosteroid level in urine
- High catecholamine level in urine
- High indoleacetic acid level in urine
- Imipramine in urine
- Lactosuria
- Lipiduria
- Mannoheptulosuria
- Norepinephrine level above reference range
- Paraquat in urine
- Phenothiazine in urine
- Porphobilinogen in urine - finding
- Porphyrins in urine - finding
- Urine 17 ketogenic steroid above reference range
- Urine 17 ketogenic steroid level outside reference range
- Urine adrenalin above reference range
- Urine adrenalin level outside reference range
- Urine norepinephrine above reference range
- Urine norepinephrine level outside reference range
- Urine novel psychoactive substance detected
- Urine urate outside reference range
- Urine vanillylmandelic acid above reference range
- Vanillylmandelic acid level above reference range
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Elevated urine levels of catecholamines
- Elevated urine levels of indoleacetic acid
- Elevated urine levels of 17-ketosteroids
- Elevated urine levels of steroids
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Abnormal, abnormality, abnormalities - See Also: Anomaly;
- urine (constituents) - R82.90
- drugs - R82.5
- indoleacetic acid - R82.5
- catecholamine - R82.5
- indoleacetic acid - R82.5
- 17-ketosteroids - R82.5
- steroids - R82.5
- vanillylmandelic acid (VMA) - R82.5
- Findings, abnormal, inconclusive, without diagnosis - See Also: Abnormal;
- 17-ketosteroids, elevated - R82.5
- catecholamines - R82.5
- indoleacetic acid, elevated - R82.5
- vanillylmandelic acid (VMA), elevated - R82.5
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Abnormal, abnormality, abnormalities
- urine (constituents)
- drugs
- Elevated, elevation
- indoleacetic acid
- Elevated, elevation
- urine level of
- catecholamine
- Elevated, elevation
- urine level of
- indoleacetic acid
- Elevated, elevation
- urine level of
- 17-ketosteroids
- Elevated, elevation
- urine level of
- steroids
- Elevated, elevation
- urine level of
- vanillylmandelic acid (VMA)
- Findings, abnormal, inconclusive, without diagnosis
- 17-ketosteroids, elevated
- Findings, abnormal, inconclusive, without diagnosis
- catecholamines
- Findings, abnormal, inconclusive, without diagnosis
- indoleacetic acid, elevated
- Findings, abnormal, inconclusive, without diagnosis
- vanillylmandelic acid (VMA), elevated
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Urine and Urination
Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert R82.5 to ICD-9-CMHistory
Code HistoryHistory
Questions About R82.5Overview
Is R82.5 (Other and unspecified abnormal findings in urine) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report elevated urine levels of drugs, medicaments and biological substances on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does R82.5 group to?
When elevated urine levels of drugs, medicaments and biological substances is the principal diagnosis on an inpatient stay, it groups to MS-DRG 695, 696, with relative weights from 0.6890 to 1.1438 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R82.5 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the elevated urine levels of drugs, medicaments and biological substances is established, that condition takes the principal position instead.
What is the ICD-9 equivalent of R82.5?
Under the General Equivalence Mappings, elevated urine levels of drugs, medicaments and biological substances converts to ICD-9-CM 791.9 (abn urine findings NEC) and 796.0 (abn toxicologic finding). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
