2026 ICD-10-CM Diagnosis Code R45.3Demoralization and apathy
ICD-10-CM Codes›R00–R99›R40-R46›R45
- Billable — Valid for Submission
- Not Chronic
R45.3 is a billable ICD-10-CM diagnosis code for demoralization and apathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as demoralization. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Symptoms of mental and substance use conditions.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Demoralization
- Indifference
- Lack of emotional response
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Type 1 Excludes
- anhedonia R45.84
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Apathy
- Demoralization
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Demoralization
weakening of hope, courage, or confidence.
Patient EducationClinical
Depression
Depression is more than a feeling of being sad or irritable for a few days. It's a serious mood disorder. As one of the most common mental disorders in the United States, depression can affect how you think, feel, and your everyday life.
The full article covers:
- What is depression?
- What are the different types of depression?
- What causes depression?
- Who is at risk of depression?
- What are the symptoms of depression?
- How is depression diagnosed?
- What are the treatments for depression?
- Can depression be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert R45.3 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About R45.3Overview
Is R45.3 (Symptoms and signs involving emotional state) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report demoralization and apathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Can R45.3 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the demoralization and apathy is established, that condition takes the principal position instead.
What is the ICD-9 equivalent of R45.3?
Under the General Equivalence Mappings, demoralization and apathy converts to ICD-9-CM 799.25 (demoralization & apathy). The mapping is a direct match.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
