ICD-10-CM Code R45.1

Restlessness and agitation

Version 2020 Billable Code No Valid Principal Dx

Valid for Submission

R45.1 is a billable code used to specify a medical diagnosis of restlessness and agitation. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code R45.1 might also be used to specify conditions or terms like agitated wandering, aimless movement, aimless overactivity, constant movement, continuously shifting in seat, feeling agitated, etc

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Short Description:Restlessness and agitation
Long Description:Restlessness and agitation

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code R45.1 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Agitated wandering
  • Aimless movement
  • Aimless overactivity
  • Constant movement
  • Continuously shifting in seat
  • Feeling agitated
  • Fidgeting
  • O/E - agitated
  • Pacing up and down
  • Psychomotor agitation
  • Psychomotor agitation
  • Restlessness
  • Restlessness and agitation
  • Squirming
  • Stress and adjustment reaction
  • Stress reaction with psychomotor agitation
  • Wandering

Convert R45.1 to ICD-9

  • 307.9 - Special symptom NEC/NOS (Approximate Flag)

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)
    • Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)
      • Symptoms and signs involving emotional state (R45)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Fear and anxiety are part of life. You may feel anxious before you take a test or walk down a dark street. This kind of anxiety is useful - it can make you more alert or careful. It usually ends soon after you are out of the situation that caused it. But for millions of people in the United States, the anxiety does not go away, and gets worse over time. They may have chest pains or nightmares. They may even be afraid to leave home. These people have anxiety disorders. Types include

  • Panic disorder
  • Obsessive-compulsive disorder
  • Post-traumatic stress disorder
  • Phobias
  • Generalized anxiety disorder

Treatment can involve medicines, therapy or both.

NIH: National Institute of Mental Health

[Learn More]