2026 ICD-10-CM Diagnosis Code R45Symptoms and signs involving emotional state

ICD-10-CM Codes›R00–R99›R40-R46›R45

ICD-10-CM R45
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R45 is a non-billable ICD-10-CM category code for symptoms and signs involving emotional state, so it cannot be submitted on claims. Use a more specific code from this category instead, such as R45.0, R45.1, R45.2, and R45.3. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established.

Code Identity

ICD-10-CM Code
R45
Billable Status
No — Non-Billable Category
Code Describes
Symptoms and signs involving emotional state
Short Description
Symptoms and signs involving emotional state
Same as the full description in the CMS dataset.
Chapter
R40-R46
Symptoms and signs involving cognition, perception, emotional state and behavior

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR40-R46Symptoms and signs involving cognition, perception, emotional state and behavior
CategoryR45Symptoms and signs involving emotional state
This CodeR45Symptoms and signs involving emotional state

Specific Coding for Symptoms and signs involving emotional stateOverview

Non-specific codes like R45 require more characters. Use one of these billable codes instead:

  • Use R45.0 for Nervousness

  • Use R45.1 for Restlessness and agitation

  • Use R45.2 for Unhappiness

  • Use R45.3 for Demoralization and apathy

  • Use R45.4 for Irritability and anger

  • Use R45.5 for Hostility

  • Use R45.6 for Violent behavior

  • Use R45.7 for State of emotional shock and stress, unspecified

  • R45.8 for Other symptoms and signs involving emotional state

  • Use R45.81 for Low self-esteem

  • Use R45.82 for Worries

  • Use R45.83 for Excessive crying of child, adolescent or adult

  • Use R45.84 for Anhedonia

  • R45.85 for Homicidal and suicidal ideations

  • Use R45.86 for Emotional lability

  • Use R45.87 for Impulsiveness

  • Use R45.88 for Nonsuicidal self-harm

  • Use R45.89 for Other symptoms and signs involving emotional state

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R45Overview

Is R45 (Symptoms and signs involving emotional state) a billable code?

No. This is a category header that groups the codes for symptoms and signs involving emotional state, and headers cannot be submitted on claims. Claims for symptoms and signs involving emotional state need a more specific code from this category, such as R45.0, R45.1, and R45.2.

Can R45 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the symptoms and signs involving emotional state is established, that condition takes the principal position instead.