2027 ICD-10-CM Diagnosis Code P91.4Neonatal cerebral depression

ICD-10-CM Codes›P00–P96›P90-P96›P91

ICD-10-CM P91.4
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P91.4 is a billable ICD-10-CM diagnosis code for neonatal cerebral depression. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 13 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neonatal cerebral disorders.

For Medicare Advantage risk adjustment, P91.4 maps to CMS-HCC Category 202 (Coma, Brain Compression/Anoxic Damage) under the V28 model, adding a risk factor of about 0.543 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
P91.4
Billable Status
Yes — Valid for Submission
Code Describes
Neonatal cerebral depression
Short Description
Neonatal cerebral depression
Same as the full description in the CMS dataset.
Parent Code
Other disturbances of cerebral status of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP90-P96Other disorders originating in the perinatal period
CategoryP91Other disturbances of cerebral status of newborn
This CodeP91.4Neonatal cerebral depression

Medicare Risk Adjustment (HCC)Billing

P91.4 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 202— Coma, Brain Compression/Anoxic Damage
Payment HCC · PY 2027 one of 61 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.543
community, non-dual, aged · ranges 0.097–0.721 across segments
Hierarchy
Superseded by HCC 63, HCC 397, and HCC 398
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Part D (RxHCC)
Not mapped
P91.4 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P91.4: its own notes plus those printed at Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P91.4, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming P91.4: they are not reported together with it, unless the two conditions are unrelated.

  • P91.6 Hypoxic ischemic encephalopathy [HIE]
    Neonatal cerebral depression (P91.4)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL004
Neonatal cerebral disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P91.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
779.2 Cns dysfunction syn NB
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P91.4Overview

What is the ICD-10 code for neonatal cerebral depression?

The ICD-10-CM code for neonatal cerebral depression is P91.4 (sometimes written as P914). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P91.4 (Other disturbances of cerebral status of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neonatal cerebral depression on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P91.4 group to?

When neonatal cerebral depression is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P91.4 a CC or MCC?

CMS lists P91.4 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 13 closely related codes in its exclusion list.

What is the ICD-9 equivalent of P91.4?

Under the General Equivalence Mappings, neonatal cerebral depression converts to ICD-9-CM 779.2 (cns dysfunction syn NB). The mapping is approximate, so confirm the match fits the documentation.

What HCC is P91.4?

P91.4 (neonatal cerebral depression) maps to CMS-HCC Category 202 (Coma, Brain Compression/Anoxic Damage), commonly written as HCC 202, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It does not map to any RxHCC in the Part D prescription drug model.

Does P91.4 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, P91.4 adds a risk adjustment factor of about 0.543 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.097 to 0.721 depending on the payment segment). A more severe related category (HCC 63, HCC 397, and HCC 398) supersedes it when both are reported. See the full factor table on the HCC 202 category page.