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  6. 2024 ICD-10-CM Code P91.81
Version 2024
Non-Billable Code

2024 ICD-10-CM Diagnosis Code P91.81

Neonatal encephalopathy

ICD-10-CM Code:
P91.81
ICD-10 Code for:
Neonatal encephalopathy
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Certain conditions originating in the perinatal period
    (P00–P96)
    • Other disorders originating in the perinatal period
      (P90-P96)
      • Other disturbances of cerebral status of newborn
        (P91)

P91.81 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of neonatal encephalopathy. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Neonatal encephalopathy

Non-specific codes like P91.81 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for neonatal encephalopathy:

  • Use P91.811 for Neonatal encephalopathy in diseases classified elsewhere - BILLABLE CODE

  • Use P91.819 for Neonatal encephalopathy, unspecified - BILLABLE CODE

Clinical Information

  • GAIA Level 1 Neonatal Encephalopathy|Global Alignment of Immunization safety Assessment in pregnancy Level 1 Neonatal Encephalopathy|Level 1 Neonatal Encephalopathy

    gaia level 1 neonatal encephalopathy is defined by three criteria: first, a newborn infant (1-28 days of life) born at or beyond 35 weeks of gestation; second, an abnormal level of alertness or seizures; third, difficulty with initiating and maintaining respiration; fourth, depression of muscle tone.

  • GAIA Level 2 Neonatal Encephalopathy|Global Alignment of Immunization safety Assessment in pregnancy Level 2 Neonatal Encephalopathy|Level 2 Neonatal Encephalopathy

    gaia level 2 neonatal encephalopathy is defined by three criteria: first, a newborn infant (1 to 28 days of life) born at or beyond 35 weeks of gestation; second, an abnormal level of alertness or seizures; third, either difficulty with initiating and maintaining respiration or depression of muscle tone.

  • GAIA Level 3 Neonatal Encephalopathy|Global Alignment of Immunization safety Assessment in pregnancy Level 3 Neonatal Encephalopathy|Level 3 Neonatal Encephalopathy

    gaia level 3 neonatal encephalopathy is defined by three criteria: first, a newborn infant (1-28 days of life) born at or beyond 35 weeks of gestation; second, an abnormal level of alertness or seizures; third, none of the following: a) difficulty with initiating or maintaining respiration; b) depression of muscle tone.

  • GAIA Neonatal Encephalopathy Level of Diagnostic Certainty Terminology|Global Alignment of Immunization safety Assessment in pregnancy Neonatal Encephalopathy Level of Diagnostic Certainty

    a subset of terminology related to neonatal encephalopathy, developed by the global alignment of immunization safety assessment in pregnancy consortium to aid in monitoring and improving fetal and maternal outcomes.

  • GAIA Neonatal Encephalopathy Level of Diagnostic Certainty|Global Alignment of Immunization safety Assessment in pregnancy Neonatal Encephalopathy Level of Diagnostic Certainty|Neonatal Encephalopathy Level of Diagnostic Certainty

    a classification of maternal and fetal outcomes relating to neonatal encephalopathy, developed by the global alignment of immunization safety assessment in pregnancy, based on the extent to which the diagnosis has been confirmed.

  • Neonatal Encephalopathy

    abnormal functioning of the central nervous system in the newborn period that may be due to a variety of etiologies including hypoxia/ischemia, metabolic disturbance, or infection.

  • Severe Neonatal Encephalopathy Due to MECP2 Mutations

    an x-linked recessive condition caused by mutation(s) in the mecp2 gene, encoding methyl-cpg-binding protein 2. it is characterized by severe neonatal encephalopathy.

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018