2026 ICD-10-CM Diagnosis Code P74.421Hyperchloremia of newborn
ICD-10-CM Codes›P00–P96›P70-P74›P74
- Billable — Valid for Submission
- Not Chronic
P74.421 is a billable ICD-10-CM diagnosis code for hyperchloremia of newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as chloride disorder. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified perinatal conditions.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Chloride disorder
- Hyperchloremia
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Hyperchloremic metabolic acidosis
Type 2 Excludes
- late metabolic acidosis of the newborn P74.0
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- metabolic NEC - E87.20
- hyperchloremic, of newborn - P74.421
- Disturbance (s) - See Also: Disease;
- electrolyte - See Also: Imbalance, electrolyte;
- newborn, transitory - P74.49
- hyperchloremia - P74.421
- hyperchloremic metabolic acidosis - P74.421
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Acidosis(lactic)
- metabolic NEC
- hyperchloremic, of newborn
- Disturbance(s)
- electrolyte
- newborn, transitory
- hyperchloremia
- Disturbance(s)
- electrolyte
- newborn, transitory
- hyperchloremic metabolic acidosis
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Fluid and Electrolyte Balance
Electrolytes are minerals that have an electric charge when they are dissolved in water or body fluids, including blood. The electric charge can be positive or negative. You have electrolytes in your blood, urine (pee), tissues, and other body fluids.
The full article covers:
- What are electrolytes?
- What are the different types of electrolytes in your body?
- What is an electrolyte imbalance?
- What are the different types of electrolyte imbalances?
- How are electrolyte imbalances diagnosed?
- What are the treatments for electrolyte imbalances?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code History & ChangesHistory
Replacement P74.421 replaces the following previously assigned code(s):
- P74.4 - Other transitory electrolyte disturbances of newborn
Questions About P74.421Overview
Is P74.421 (Disturbances of chlorine balance of newborn) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report hyperchloremia of newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
