ICD-10-CM Tabular Index · Chapter 16 · FY 2026 P74

Other transitory neonatal electrolyte and metabolic disturbances (P74) ICD-10-CM

The P74 code range covers other transitory neonatal electrolyte and metabolic disturbances with 19 ICD-10-CM diagnosis codes. 14 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.

✓ Built from the official CMS FY 2026 datasetEffective Oct 1, 2025 – Sep 30, 2026
19
Diagnosis Codes
14
Billable Codes
P74
Code Range
P70–P74
Parent Section
ICD-10-CM

Codes in the P74 Range 19 codes · 14 billable

19 of 19 shown
  • P74 Other transitory neonatal electrolyte and metabolic disturbancesNon-billable
  • P74.0 Late metabolic acidosis of newborn
  • P74.1 Dehydration of newborn
  • P74.2 Disturbances of sodium balance of newbornNon-billable
  • P74.21 Hypernatremia of newborn
  • P74.22 Hyponatremia of newborn
  • P74.3 Disturbances of potassium balance of newbornNon-billable
  • P74.31 Hyperkalemia of newborn
  • P74.32 Hypokalemia of newborn
  • P74.4 Other transitory electrolyte disturbances of newbornNon-billable
  • P74.41 Alkalosis of newborn
  • P74.42 Disturbances of chlorine balance of newbornNon-billable
  • P74.421 Hyperchloremia of newborn
  • P74.422 Hypochloremia of newborn
  • P74.49 Other transitory electrolyte disturbance of newborn
  • P74.5 Transitory tyrosinemia of newborn
  • P74.6 Transitory hyperammonemia of newborn
  • P74.8 Other transitory metabolic disturbances of newborn
  • P74.9 Transitory metabolic disturbance of newborn, unspecified

Clinical Terms in This Code Range

Definitions from the National Library of Medicine for conditions coded in the P74 range.

Carbamoyl-Phosphate Synthase I Deficiency Disease

A urea cycle disorder manifesting in infancy as lethargy, emesis, seizures, alterations of muscle tone, abnormal eye movements, and an elevation of serum ammonia. The disorder is caused by a reduction in the activity of hepatic mitochondrial CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA). (Menkes, Textbook of Child Neurology, 5th ed, pp50-1)

Dehydration

The condition that results from excessive loss of water from a living organism.

Hyperammonemia

Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.

Hyperkalemia

Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)

Hyperlysinemias

A group of inherited metabolic disorders which have in common elevations of serum LYSINE levels. Enzyme deficiencies of alpha-aminoadipic semialdehyde dehydrogenase and the SACCHAROPINE DEHYDROGENASES have been associated with hyperlysinemia. Clinical manifestations include mental retardation, recurrent emesis, hypotonia, lethargy, diarrhea, and developmental delay. (From Menkes, Textbook of Child Neurology, 5th ed, p56)

Hypernatremia

Excessive amount of sodium in the blood. (Dorland, 27th ed)

Pseudohypoaldosteronism

A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION.

Rett Syndrome

An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)

About the P74 Code Range

The ICD-10 code section P74 covers a range of temporary electrolyte and metabolic disturbances that newborns can experience shortly after birth. These codes help identify specific conditions like dehydration, sodium and potassium imbalances, and metabolic acidemia in newborns.

This section includes codes for conditions such as P74.0 Late metabolic acidosis of newborn, also known as neonatal acidosis, which involves abnormal acid levels in a newborn's blood. Dehydration-related conditions are classified under P74.1 Dehydration of newborn, capturing issues from mild to severe water loss in newborns. Sodium disturbances, including P74.21 Hypernatremia and P74.22 Hyponatremia, represent abnormal high and low sodium levels, respectively, while potassium imbalances like P74.31 Hyperkalemia and P74.32 Hypokalemia denote high or low potassium. Other important codes cover alkalosis, chloride imbalances, and metabolic disorders such as P74.5 Transitory tyrosinemia and P74.6 Transitory hyperammonemia. Using the ICD-10 code for neonatal electrolyte and metabolic disturbances ensures accurate diagnosis and management of these transient but critical newborn conditions.

Questions About This Page

How many billable codes are in the P74 range?

Of the 19 codes in this range, 14 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.

What does the P74 range classify?

The range classifies other transitory neonatal electrolyte and metabolic disturbances. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.

Related References

Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.